{"product_id":"prohealth-trans-resveratrol-1000-mg-60-capsules-ph528","title":"Trans-Resveratrol Plus - 1000 mg per serving, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eSupports Brain, Cardiovascular and Joint Health\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports brain health and cognitive function\u003c\/li\u003e\n\u003cli\u003eSupports cellular and DNA health\u003c\/li\u003e\n\u003cli\u003eSupports healthy aging\u003c\/li\u003e\n\u003cli\u003eSupports heart and metabolic health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH528-_COA_Brighton_LOT_23192_2024-10-30_1.pdf?v=1733499816\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e Supports Brain Health\u003c\/strong\u003e. Research shows that resveratrol, a molecule found in red grapes and wine, may protect the brain from symptoms of brain aging, including improving memory and delaying cognitive decline. The neuroprotective effects of resveratrol come from its sirtuin-activating, inflammation-regulating, mitochondrial-supporting and antioxidant activity. (1-3)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Cellular and DNA Health\u003c\/strong\u003e. Resveratrol acts as a potent antioxidant, which reduces harmful oxidative stress. It also activates genes called sirtuins. Healthy sirtuin activity helps to fight cellular senescence, support DNA repair, boost mitochondrial function and generate cellular energy through ATP production. (3,4)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Healthy Aging\u003c\/strong\u003e. Resveratrol activates SIRT1, often referred to as the \"longevity gene.\" Healthy older adults tend to have higher levels of SIRT1 activity, and SIRT1 overexpression can increase lifespan in worms and animals. In humans, SIRT1 supports healthy aging and longevity. (5,6)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Joint Health\u003c\/strong\u003e. Due to its role in supporting healthier inflammatory responses and modulating oxidative stress, resveratrol has exhibited joint-protective effects. (7)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Heart Health\u003c\/strong\u003e. Resveratrol is well-known for its link to supporting cardiovascular health. Research has found that resveratrol benefits endothelial function, blood vessel health and blood pressure by boosting SIRT1 activity, reducing oxidative stress and increasing nitric oxide production. (8,9)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Metabolic Health\u003c\/strong\u003e. Resveratrol activates SIRT1, which has been studied for its role in supporting healthier glucose metabolism. People with reduced SIRT1 expression tend to have higher blood sugar, poor glucose control and metabolic disorders. (10)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Salehi B, Mishra AP, Nigam M, et al. Resveratrol: A Double-Edged Sword in Health Benefits. Biomedicines. 2018;6(3):91. Published 2018 Sep 9. doi:10.3390\/biomedicines6030091 \u003cbr\u003e\u003cbr\u003e2. Bastianetto S, Ménard C, Quirion R. Neuroprotective action of resveratrol. Biochim Biophys Acta. 2015;1852(6):1195-1201. doi:10.1016\/j.bbadis.2014.09.011 \u003cbr\u003e\u003cbr\u003e3. Moraes DS, Moreira DC, Andrade JMO, Santos SHS. Sirtuins, brain and cognition: A review of resveratrol effects. IBRO Rep. 2020;9:46-51. Published 2020 Jun 26. doi:10.1016\/j.ibror.2020.06.004 \u003cbr\u003e\u003cbr\u003e4. Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem. 2005;280(17):17187-17195. doi:10.1074\/jbc.M501250200 \u003cbr\u003e\u003cbr\u003e5. Kilic U, Gok O, Erenberk U, et al. A remarkable age-related increase in SIRT1 protein expression against oxidative stress in elderly: SIRT1 gene variants and longevity in human. PLoS One. 2015;10(3):e0117954. Published 2015 Mar 18. \u003cbr\u003e\u003cbr\u003e6. Salminen A, Kaarniranta K. SIRT1: regulation of longevity via autophagy. Cell Signal. 2009;21(9):1356-1360. doi:10.1016\/j.cellsig.2009.02.014 \u003cbr\u003e\u003cbr\u003e7. Nguyen C, Savouret JF, Widerak M, Corvol MT, Rannou F. Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review. Nutrients. 2017;9(1):45. Published 2017 Jan 6. doi:10.3390\/nu9010045 \u003cbr\u003e\u003cbr\u003e8. Marques BCAA, Trindade M, Aquino JCF, et al. Beneficial effects of acute trans-resveratrol supplementation in treated hypertensive patients with endothelial dysfunction. Clin Exp Hypertens. 2018;40(3):218-223. doi:10.1080\/10641963.2017.1288741 \u003cbr\u003e\u003cbr\u003e9. Bonnefont-Rousselot D. Resveratrol and Cardiovascular Diseases. Nutrients. 2016;8(5):250. Published 2016 May 2. doi:10.3390\/nu8050250 \u003cbr\u003e\u003cbr\u003e10. Hou CY, Tain YL, Yu HR, Huang LT. The Effects of Resveratrol in the Treatment of Metabolic Syndrome. Int J Mol Sci. 2019;20(3):535. Published 2019 Jan 28. doi:10.3390\/ijms20030535\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBest Form of Resveratrol.\u003c\/strong\u003e Other resveratrol supplements are typically composed of 50% trans-resveratrol and 50% cis-resveratrol. ProHealth uses trans-resveratrol because it has a higher biological availability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNatural Source.\u003c\/strong\u003e ProHealth’s trans-resveratrol is pure and natural for the highest quality.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigher Dose.\u003c\/strong\u003e Each serving contains 1000 mg pure and natural trans-resveratrol.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formulation.\u003c\/strong\u003e Compared to other products, ProHealth Longevity’s Trans-Resveratrol also includes 420 mg of a proprietary blend of quercetin, organic red wine extract, organic decaf green tea extract and BioPerine® to support absorption. These select co-factors and BioPerine® included in this formula can improve absorption and increase C-max blood levels by up to 1544% compared to regular resveratrol supplements.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdditional Certifications.\u003c\/strong\u003e Non-GMO, Vegan and Gluten-Free\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\" style=\"height: 174.883px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth align=\"left\" colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003eServing Size: 2 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; height: 17.15px;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 17.15px;\"\u003ePure  Veri-te® Trans-Resveratrol\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 68.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 68.6px;\"\u003e\n\u003cstrong\u003eProprietary Blend\u003c\/strong\u003e\u003cbr\u003eQuercetin Dihydrate (from \u003cem\u003eSophora japonica\u003c\/em\u003e Flower Extract), Red Wine (\u003cem\u003eVitis vinifera\u003c\/em\u003e) Fruit Extract, Green Tea Leaf Extract, BioPerine® Black Pepper Fruit Extract (95% Piperine)®\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 68.6px;\"\u003e420 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 68.6px;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.08.25\u003cbr\u003eVeri-te® is a registered trademark of the Lallemand group. BioPerine® is a registered trademark of Sabinsa, Co.\u003cbr\u003e\u003cbr\u003e** Herbal products such as this are likely to have minor color variation from batch to batch because of the geographical and seasonal variations of the raw material.\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), rice flour.\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake two (2) capsules per day, with food, preferably in the morning.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":45096814117024,"sku":"PH528","price":31.08,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH528_175CC_FRNT_600x600-REV0825-1.png?v=1770653310","url":"https:\/\/wholesale.prohealth.com\/products\/prohealth-trans-resveratrol-1000-mg-60-capsules-ph528","provider":"ProHealth Wholesale","version":"1.0","type":"link"}