{"product_id":"prohealth-s-acetyl-glutathione-300-mg-60-capsules-ph497","title":"S-Acetyl Glutathione - 300 mg, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eSupports detoxification, brain health and cellular functions.\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy cell function and healthy aging\u003c\/li\u003e\n\u003cli\u003eSupports liver detoxification\u003c\/li\u003e\n\u003cli\u003eSupports the brain and nervous system\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH497_-_COA_Brighton_LOT_23837_2026.08.11.pdf?v=1792680778\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular Health.\u003c\/strong\u003e Glutathione is our body’s most abundant antioxidant, playing a critical role in protecting the body from oxidative stress. Glutathione helps to regulate several cellular events, such as gene expression, protein and DNA synthesis, immune response and cell growth. In addition to being an antioxidant itself, glutathione is also a cofactor for several other antioxidant enzymes\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Detoxification.\u003c\/strong\u003e Glutathione supports both phase 1 and phase 2 detoxification in the liver, helping to neutralize and excrete harmful toxins. Glutathione not only binds to toxins before they can bind to and damage cells, but it also transforms toxins into a water-soluble form for further filtering and easy excretion through the urinary system. Dysfunctional detoxification pathways can lead to liver damage, DNA damage and increased cellular stress.\u003csup\u003e4\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Healthy Aging.\u003c\/strong\u003e Glutathione deficiency contributes to oxidative stress, which can accelerate aging and the development of age-related disorders. Our mitochondria—the cells’ energy production centers—are dependent on glutathione, which can cross mitochondrial membranes and minimize reactive oxygen species (ROS) buildup. Healthy mitochondrial function is vital for healthy aging.\u003csup\u003e5\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Brain and Nervous System Health.\u003c\/strong\u003e Glutathione is necessary for neutralizing ROS in the brain, which can lead to poor cognitive function. Research shows that reduced glutathione levels in the brain are linked to the development of neurological conditions.\u003csup\u003e6, 7\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Glutathione metabolism and its implications for health. J Nutr. 2004;134(3):489-492. doi:10.1093\/jn\/134.3.489 \u003cbr\u003e\u003cbr\u003e2. Chatterjee A. Reduced glutathione: a radioprotector or a modulator of DNA-repair activity?. Nutrients. 2013;5(2):525-542. Published 2013 Feb 7. doi:10.3390\/nu5020525 doi:10.3390\/nu5020525 \u003cbr\u003e\u003cbr\u003e3. Forman HJ, Zhang H, Rinna A. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med. 2009;30(1-2):1-12. doi:10.1016\/j.mam.2008.08.006 \u003cbr\u003e\u003cbr\u003e4. Pizzorno J. Glutathione!. Integr Med (Encinitas). 2014;13(1):8-12. PMID: 26770075 \u003cbr\u003e\u003cbr\u003e5. Marí M, Morales A, Colell A, García-Ruiz C, Fernández-Checa JC. Mitochondrial glutathione, a key survival antioxidant. Antioxid Redox Signal. 2009;11(11):2685-2700. doi:10.1089\/ARS.2009.2695 \u003cbr\u003e\u003cbr\u003e6. Dringen R. Metabolism and functions of glutathione in brain. Prog Neurobiol. 2000;62(6):649-671. doi:10.1016\/s0301-0082(99)00060-x \u003cbr\u003e\u003cbr\u003e7. Mandal PK, Saharan S, Tripathi M, Murari G. Brain glutathione levels--a novel biomarker for mild cognitive impairment. Biol Psychiatry. 2015;78(10):702-710. doi:10.1016\/j.biopsych.2015.04.005 \u003cbr\u003e\u003cbr\u003e8. Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL. Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem. 2009;390(3):191-214. doi:10.1515\/BC.2009.033 \u003cbr\u003e\u003cbr\u003e9. Di Paola R, Modafferi S, Siracusa R, et al. S-Acetyl-Glutathione Attenuates Carbon Tetrachloride-Induced Liver Injury by Modulating Oxidative Imbalance and Inflammation. Int J Mol Sci. 2022;23(8):4429. Published 2022 Apr 17.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eGlutathione functions extensively in tissues and organs throughout the body. \u003c\/li\u003e\n\u003cli\u003eIt plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function. \u003c\/li\u003e\n\u003cli\u003eMany factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients—such as glutathione—that provide antioxidant activity. \u003c\/li\u003e\n\u003cli\u003eThis may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete biotransformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health. (8) \u003c\/li\u003e\n\u003cli\u003eMuch information related to mitochondrial health has surfaced in scientific literature. Mitochondria, the energy-producing powerhouses of cells, are also the primary intracellular site of oxygen consumption and the major source of reactive oxygen species (ROS). \u003c\/li\u003e\n\u003cli\u003eS-acetyl glutathione has been shown to cross the membrane of the mitochondria, increasing the organelle's activity and minimizing ROS.(5)\u003c\/li\u003e\n\u003cli\u003eReduction of ROS is associated with maintaining mitochondrial integrity and function, and improved mitochondrial health is believed to support overall health and energy.  \u003c\/li\u003e\n\u003cli\u003eUse of stomach acid-resistant capsules (DRcaps) further protect stability. Laboratory data showed that S-acetyl glutathione increased intracellular glutathione and had a positive effect on many oxidative stress biomarkers. (9)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" style=\"font-weight: bold;\" class=\"smalltext\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eEmothion® S-Acetyl L-Glutathione\u003cbr\u003e(from Liposomal Glutathione)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e300 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.06.25\n\u003cp\u003eEmothion® is a registered trademark of Gnosis S.p.A.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e\u003cspan\u003e \u003c\/span\u003eSunflower lecithin, hypromellose (capsule), magnesium stearate.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take one (1) capsule per day without food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF  CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cp\u003e\u003cstrong\u003eIncreased Bioavailability.\u003c\/strong\u003e Traditional glutathione supplements have poor absorption in the body. The S-acetyl glutathione in Emothion® is in crystalline form, which has a quicker dissolution rate and more efficient absorption than other glutathione supplements.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBetter Form.\u003c\/strong\u003e Many glutathione supplements use L-glutathione. ProHealth uses S-acetyl glutathione, a derivative of glutathione that is more bioavailable, can cross mitochondrial membranes and can increase glutathione levels inside cells better.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHigher Dose.\u003c\/strong\u003e Typical glutathione supplements contain 100 mg, whereas ProHealth’s S-acetyl glutathione contains 300 mg per serving.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStability Protection.\u003c\/strong\u003e The use of stomach acid-resistant capsules (DRcaps) further protects glutathione’s stability.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMeets US Pharmacopeia Standards.\u003c\/strong\u003e Our S-acetyl glutathione ingredients meet US Pharmacopeia standards.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFree of Unwanted Ingredients.\u003c\/strong\u003e S-acetyl glutathione doesn’t contain yeast, wheat, gluten, sugar, salt, dairy, eggs, peanuts, tree nuts, fish, shellfish, soy, corn, dye or preservatives.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":45096845672608,"sku":"PH497","price":74.72,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH497_175ML_FRNT_600x600_8e92bf32-1c2a-4e34-bb23-749f50797ccc.png?v=1771950114","url":"https:\/\/wholesale.prohealth.com\/products\/prohealth-s-acetyl-glutathione-300-mg-60-capsules-ph497","provider":"ProHealth Wholesale","version":"1.0","type":"link"}