{"product_id":"prohealth-nmn-powder-1000-mg-30-grams-ph579","title":"NMN Pro™ Powder - Uthever® NMN, 30 grams","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\n\u003ch2\u003eHelps combat aging, improves heart health and promotes muscle strength\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eNMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.\u003c\/li\u003e\n\u003cli\u003eNicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.\u003c\/li\u003e\n\u003cli\u003eNMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability. In this way, NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered into the bloodstream.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH579_-_COA_Brighton_LOT_26053_2026.04.13_2.pdf?v=1792161758\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Longevity.\u003c\/strong\u003e Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies. (1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBlood Sugar Regulation.\u003c\/strong\u003e As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Metabolism and Healthy Weight.\u003c\/strong\u003e Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight. (3,4,5)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Healthy Cognition:\u003c\/strong\u003e Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction. (6,7)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Healthy Skin:\u003c\/strong\u003e In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. (8,9)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016\/j.cmet.2016.09.004 \u003cbr\u003e\u003cbr\u003e 2. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016\/j.bbadis.2021.166287 \u003cbr\u003e\u003cbr\u003e 3. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080\/08982104.2020.1820521 \u003cbr\u003e\u003cbr\u003e 4. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1\/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016\/j.jphotobiol.2021.112238 \u003cbr\u003e\u003cbr\u003e 5. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390\/nu14040755 \u003cbr\u003e\u003cbr\u003e 6. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007\/s11357-020-00165-5 \u003cbr\u003e\u003cbr\u003e 7. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186\/s12970-021-00442- \u003cbr\u003e\u003cbr\u003e 8. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016\/j.cmet.2016.09.013 \u003cbr\u003e\u003cbr\u003e 9. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016\/j.redox.2019.101192 \u003cbr\u003e\u003cbr\u003e 10. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016\/j.brainres.2016.04.060 \u003cbr\u003e\u003cbr\u003e 11. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016\/j.cmet.2011.08.014 \u003cbr\u003e\u003cbr\u003e 12. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126\/science.abe9985\u003c\/p\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\" colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Level Scoop\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 30\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eUthever® β-Nicotinamide Mononucleotide (NMN)\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value not established.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV. 10.23\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN: \u003c\/strong\u003eDairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Place 1 scoop under the tongue to dissolve, then swallow, or mix in water, or as recommended by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. Package filled by weight, not volume. \u003cstrong data-mce-fragment=\"1\"\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your health care provider before using this product. \u003cstrong\u003e \u003cbr\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eNicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient. NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, brain health, heart health, body weight and gene expression.\u003c\/li\u003e\n\u003cli\u003eNMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability. In this way, NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered into the bloodstream.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnly Clincially-Proven NMN\u003c\/strong\u003e. ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Delivery Method.\u003c\/strong\u003e NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolvent-Free.\u003c\/strong\u003e Compared to other NMN products, ours is made without any chemical solvents.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong\u003eBe Aware of Fake NMN:\u003c\/strong\u003e Fraudulent companies are always attempting to out-price competitors by using NMN fake ingredients to gain market share, which is not fair to you, the consumer, or the reputable companies, like ProHealth that spends time and resources to ensure a safe and pure NMN product.\u003c\/div\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":45096783675552,"sku":"PH579","price":55.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH579_FRNT_120ML_Jar_600x600_9739759f-634d-4d24-8f41-8dcbab4287d0.png?v=1771891430","url":"https:\/\/wholesale.prohealth.com\/products\/prohealth-nmn-powder-1000-mg-30-grams-ph579","provider":"ProHealth Wholesale","version":"1.0","type":"link"}