{"product_id":"prohealth-longevity-fisetin-pro-longevity-60-capsules-ph590","title":"Fisetin Pro Longevity - 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eSupport and Maintain Healthy Brain Function\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports longevity\u003c\/li\u003e\n\u003cli\u003ePromotes brain health\u003c\/li\u003e\n\u003cli\u003eEnhances cellular health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH590_-_COA_Brighton_LOT_26038_2025-12-01-1_2.pdf?v=1765471227\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Longevity\u003c\/strong\u003e. Fisetin supports longevity by aiding in the removal of senescent cells from the body. (1) Senescent cells, also known as zombie cells, accumulate as we age and contribute to oxidative stress, inflammation and accelerated cellular aging. Research shows that removing senescent cells extends lifespan in animals. (1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Brain Health\u003c\/strong\u003e. Research shows that fisetin supplementation may reduce symptoms of age-related brain health decline. (2) Functioning as an antioxidant to reduce neuroinflammation, fisetin has been shown to enhance learning and memory. (2) Additionally, fisetin may prevent brain cell death associated with brain aging. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances Cellular Health\u003c\/strong\u003e. Oxidative stress contributes to cellular damage and accelerated cellular aging. While inflammation and oxidative stress are natural, high levels of oxidative stress and inflammation dramatically reduce longevity. Research shows that fisetin supplementation may reduce oxidative stress and inflammation due to its antioxidant effects, thus promoting longevity. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Yousefzadeh MJ, Zhu Y, McGowan SJ, et al. Fisetin is a senotherapeutic that extends health and lifespan. EBioMedicine. 2018;36:18-28. doi:10.1016\/j.ebiom.2018.09.015 \u003cbr\u003e\u003cbr\u003e2. Nabavi SF, Braidy N, Habtemariam S, Sureda A, Manayi A, Nabavi SM. Neuroprotective Effects of Fisetin in Alzheimer's and Parkinson's Diseases: From Chemistry to Medicine. Curr Top Med Chem. 2016;16(17):1910-1915. doi:10.2174\/1568026616666160204121725 \u003cbr\u003e\u003cbr\u003e3. Jiang K, Yang J, Xue G, Dai A, Wu H. Fisetin Ameliorates the Inflammation and Oxidative Stress in Lipopolysaccharide-Induced Endometritis. J Inflamm Res. 2021;14:2963-2978. Published 2021 Jul 5. doi:10.2147\/JIR.S314130\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003e\n\u003cstrong\u003eProprietary Lifespan Absorption Blend™\u003c\/strong\u003e \u003cbr\u003e  Glucomannan (from Konjac Root), Marshmallow Root Powder, Green\u003cbr\u003e  Tea Leaf Extract (45% EGCG), Long Pepper Fruit Extract (20:1), Quercetin\u003cbr\u003e  (from \u003cem\u003eSophora japonica\u003c\/em\u003e Flower Extract), Turmeric Root Extract (95% Curcuminoids)s \u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e350 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eFisetin (from \u003cem\u003eRhus succedanea\u003c\/em\u003e \u003cbr\u003e  Stem Extract)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e125 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eMedium-Chain Triglycerides (MCT) Oil\u003cbr\u003e  Powder (from Coconut)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e25 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.07.25\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e Vegetable cellulose (capsule), brown rice flour. \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take on (1) or two (2) capsules per day. \u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eFisetin is one of the most potent senolytic compounds in existence. Senolytics are defined as nutrients that aid in the removal of senescent cells from the body. As senescent cells accumulate, oxidative stress and longevity decrease.\u003c\/li\u003e\n\u003cli\u003eDNA damage accelerates cellular aging. Fisetin may protect against DNA damage and promote DNA repair.\u003c\/li\u003e\n\u003cli\u003eFisetin exhibits powerful antioxidant effects, reducing oxidative stress and inflammation.\u003c\/li\u003e\n\u003cli\u003eAs we age, our brain cells degrade due to oxidative stress—the buildup of inflammatory compounds called reactive oxygen species. As an antioxidant, fisetin fights off oxidative stress that damages our cells, including neurons. Fisetin also has exhibited beneficial effects on age-related changes in the brain by triggering signaling pathways that promote brain cell growth and neuronal integrity.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formulation.\u003c\/strong\u003e The majority of fisetin products have poor absorption. To help, we added a Proprietary Lifespan Absorption Blend™ to dramatically enhance bioavailability and efficacy and support various aspects of health.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eIncreased Absorption.\u003c\/strong\u003e To further enhance absorption, we included MCT Oil Powder. Adding a fat to the product helps increases the body’s ability to utilize fisetin.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupported for Daily Use.\u003c\/strong\u003e Compared to other fisetin products that are intended to be used 1-2 times per week, our formula is safe enough to be used daily.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":45096779546784,"sku":"PH590","price":37.0,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH590_FRNT_250CC-600x600-REV0725.png?v=1788991462","url":"https:\/\/wholesale.prohealth.com\/products\/prohealth-longevity-fisetin-pro-longevity-60-capsules-ph590","provider":"ProHealth Wholesale","version":"1.0","type":"link"}