{"product_id":"prohealth-enzogenol-pine-bark-extract-250-mg-60-capsules-ph624","title":"Enzogenol® Pine Bark Extract - 250 mg per serving, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eEnzogenol Pine Bark Extract is a powerful antioxidant which promotes longevity and overall wellness, especially for those over 40.\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003ePromotes cardiovascular health\u003c\/li\u003e\n\u003cli\u003eSupports cognitive function and brain plasticity\u003c\/li\u003e\n\u003cli\u003eImproves skin health and appearance\u003c\/li\u003e\n\u003cli\u003eProtects joints from wear and tear\u003c\/li\u003e\n\u003cli\u003eEnhances immunity and athletic recovery\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH624_-_COA_Brighton_LOT_26009_2025.08.13.pdf?v=1759941077\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Cardiovascular Health.\u003c\/strong\u003e Pine bark extract contains antioxidants, such as proanthocyanidins, that may contribute to maintaining heart health in older adults by improving blood flow and increasing plasma antioxidant capacity. In addition, its polyphenol content has been shown to modulate LDL cholesterol levels in human studies. (1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cognitive Function and Brain Plasticity.\u003c\/strong\u003ePine bark extract has been shown to promote autophagy, an internal process that removes dysfunctional cells, which may be beneficial for brain function and plasticity by maintaining neuron health and facilitating the formation of new neural connections. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImproves Skin Health and Appearance.\u003c\/strong\u003e Pine bark extract is rich in proanthocyanins, compounds that may support collagen production and improve skin health by protecting against UV damage, promoting skin elasticity, and reducing the appearance of age-related skin issues. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtects Joints from Wear and Tear. \u003c\/strong\u003e The antioxidants in pine bark extract may help reduce joint discomfort and protect joints from age-related damage by neutralizing free radicals that cause oxidative stress and contribute to the breakdown of cartilage. (4,5)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImproves DNA Integrity.\u003c\/strong\u003e Pine bark extract supports DNA damage reduction as shown in a 12-week study of human subjects via enhanced capacity to control free radical damage in cells. (3, 6)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eMay Improve Athletic Performance and Recovery.\u003c\/strong\u003e Some research suggests that pine bark extract could enhance cellular antioxidant levels, possibly promoting better athletic performance and recovery by reducing muscle fatigue and supporting muscle repair processes. (7)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Nakayama S, Kishimoto Y, Saita E, et al. Pine bark extract prevents low-density lipoprotein oxidation and regulates monocytic expression of antioxidant enzymes. Nutrition Research. 2015;35(1):56-64. doi:10.1016\/j.nutres.2014.10.010 \u003cbr\u003e\u003cbr\u003e2. Theadom A, Mahon S, Barker-Collo S, et al. Enzogenol for cognitive functioning in traumatic brain injury: a pilot placebo-controlled RCT. Eur J Neurol. 2013;20(8):1135-1144. doi:10.1111\/ene.12099 \u003cbr\u003e\u003cbr\u003e3. Senthilmohan ST, Zhang J, Stanley RA. Effects of flavonoid extract Enzogenol® with vitamin C on protein oxidation and DNA damage in older human subjects. Nutrition Research. 2003;23(9):1199-1210. doi:10.1016\/S0271-5317(03)00127-1 \u003cbr\u003e\u003cbr\u003e4. Yazaki Y. Utilization of flavonoid compounds from bark and wood: a review. Natural Product Communications. 2015;10(3):1934578X1501000. doi:10.1177\/1934578X1501000333 \u003cbr\u003e\u003cbr\u003e5. Li YY, Feng J, Zhang XL, Cui YY. Pine bark extracts: nutraceutical, pharmacological, and toxicological evaluation. J Pharmacol Exp Ther. 2015;353(1):9-16. doi:10.1124\/jpet.114.220277 \u003cbr\u003e\u003cbr\u003e6. Kim DS, Kim MS, Kang SW, Sung HY, Kang YH. Pine bark extract enzogenol attenuated tumor necrosis factor-α-induced endothelial cell adhesion and monocyte transmigration. J Agric Food Chem. 2010;58(11):7088-7095. doi:10.1021\/jf1005287 \u003cbr\u003e\u003cbr\u003e7. O’Callaghan YC, Drummond E, O’Gorman DM, O’Brien NM. Antioxidant and pro-apoptotic effects of marine-derived, multi-mineral aquamin supplemented with a pine bark extract, enzogenol, and a green tea extract, sunphenon. Journal of Medicinal Food. 2013;16(10):920-926. doi:10.1089\/jmf.2012.0258 \u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eEnzogenol® Pine Bark Extract contains proanthocyanins, compounds that provide various health benefits, such as supporting cardiovascular health, brain function and skin health by promoting healthy blood flow, neuronal activity and collagen production, respectively. (5, 6, 8)\u003c\/li\u003e\n\u003cli\u003eThese compounds also play a role in maintaining cellular energy production and function, potentially supporting immunity and overall wellness by enhancing mitochondrial activity and reducing oxidative stress. (8)\u003c\/li\u003e\n\u003cli\u003ePine bark extract has been shown to exhibit positive effects on inflammatory pathways and support a healthy immune system. Research suggests that the proanthocyanins in pine bark extract can inhibit the production of pro-inflammatory cytokines and the activation of nuclear factor-kappa B (NF-κB), a protein complex that plays a central role in regulating the immune response to infection and inflammation. (7, 8)\u003c\/li\u003e\n\u003cli\u003eEnzogenol® Pine Bark Extract may enhance athletic performance and recovery by reducing exercise-induced oxidative stress. The potent antioxidant properties of the proanthocyanins found in pine bark extract can help neutralize free radicals generated during intense physical activity, protecting cells from damage and promoting faster recovery. Additionally, pine bark extract has been shown to improve blood flow and oxygen delivery to muscles, which can support endurance and overall performance. Research suggests that supplementation with pine bark extract may lead to reduced muscle soreness and faster recovery times, enabling athletes to maintain a consistent training regimen with less downtime. (4, 5, 6)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\" style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 2 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eEnzogenol® Pine Bark Extract \u003cem\u003e(Pinus radiata)\u003c\/em\u003e\n\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap;\" class=\"smalltext\"\u003e250 mg\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap;\" class=\"smalltext\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e† Daily value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.03.24\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eOrganic rice our, vegetable capsule.\u003cstrong\u003e \u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eDOES NOT CONTAIN:\u003c\/strong\u003e Dairy, egg, soy, wheat, gluten, peanuts, tree nuts, fish, shellfish, sesame.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take 2 capsules per day, or as directed by your healthcare professional.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBetter Absorption.\u003c\/strong\u003e Our Enzogenol® Pine Bark Extract is formulated for optimal absorption, ensuring you receive the full benefits of this natural supplement by maximizing the bioavailability of its active compounds.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigher Diversity of Compounds:\u003c\/strong\u003e Our Enzogenol® Pine Bark Extract, thanks to its mechanical fractionation process, offers a wider range of beneficial compounds. This higher diversity contributes to its enhanced antioxidant activity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigher Concentrations.\u003c\/strong\u003e Our Enzogenol® Pine Bark Extract is standardized at a higher concentration than other pine bark extracts available, so you get the benefits of more active compounds while taking a smaller dose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-Supported.\u003c\/strong\u003e Enzogenol® Pine Bark Extract is supported by numerous peer-reviewed, double-blind, placebo-controlled studies in humans, indicating its potential to promote longevity, heart health, and overall wellness in older adults.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":48313679478944,"sku":"PH624","price":49.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH624_175ML_FRNT_600x600_7d0962ad-12c1-4a79-8f7d-0836264f43b7.png?v=1772477493","url":"https:\/\/wholesale.prohealth.com\/products\/prohealth-enzogenol-pine-bark-extract-250-mg-60-capsules-ph624","provider":"ProHealth Wholesale","version":"1.0","type":"link"}