{"product_id":"prohealth-alpha-lipoic-acid-1000-mg-30-capsules-ph644","title":"Alpha Lipoic Acid - 1000 mg per serving, 60 capsules","description":"\u003cdetails\u003e\n\u003ch2\u003eAlpha Lipoic Acid\u003c\/h2\u003e\n\u003cp\u003eAlpha lipoic acid (ALA) is a powerful antioxidant that safeguards each of the cells in our body, supporting longevity by reducing oxidative stress and protecting against cellular damage. Research shows alpha lipoic acid protects against age-related health decline of the heart, brain and skin.\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eSupports cellular health by reducing oxidative stress\u003c\/li\u003e\n\u003cli\u003ePromotes energy production by supporting mitochondrial health\u003c\/li\u003e\n\u003cli\u003eNormalizes blood sugar levels by improving insulin sensitivity\u003c\/li\u003e\n\u003cli\u003eProtects the heart from free radical damage\u003c\/li\u003e\n\u003cli\u003eEnhances cognitive health by protecting neurons from oxidative damage\u003c\/li\u003e\n\u003cli\u003eImproves skin health by aiding in collagen synthesis\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH644_-_COA_Brighton__LOT_2510147_2025-12-01.pdf?v=1765467308\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cbr\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular Health. \u003c\/strong\u003eAlpha lipoic acid (ALA) functions as a powerful antioxidant, protecting each of the cells in our body from oxidative damage. (1) Studies show that oxidative damage is a key contributor to age-related health decline and decreased longevity. (2) ALA further supports cellular health by aiding in mitochondrial biogenesis (the creation of new mitochondria), which is critical for ATP (cellular energy) production. (3)\u003c\/p\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003eRegulates Blood Sugar.\u003c\/strong\u003e Research shows alpha lipoic acid exhibits blood-sugar regulating effects by increasing the uptake of glucose into cells and increasing insulin sensitivity. (4) A 2022 meta-analysis of 16 randomized controlled trials concluded alpha lipoic acid supplementation significantly reduces fasting blood glucose and Hemoglobin A1C. (5)\u003c\/p\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances Heart Health. \u003c\/strong\u003eBy reducing oxidative stress, alpha lipoic acid offers protection against age-related decline of heart health. A 2022 randomized controlled trial involving 46 participants found that 12 weeks of alpha lipoic acid supplementation offers additional cardio-protection by significantly reducing triglycerides and total cholesterol. (6)\u003c\/p\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Cognitive Health. \u003c\/strong\u003eResearch shows that oxidative stress contributes to many of the symptoms of brain aging, including cognitive dysfunction and reduced memory. (7) Animal studies indicate alpha lipoic acid has neuroprotective effects by reducing markers of oxidative stress in the brain. (8)\u003c\/p\u003e\n\u003cbr\u003e\n\u003cp\u003e\u003cstrong\u003eImproves Skin Health. \u003c\/strong\u003eA key contributor to skin aging is the decline in collagen production that occurs after age 40. Alpha lipoic acid supports healthy collagen synthesis by aiding in the recycling of vitamin C, which is a critical nutrient that promotes collagen production within the body. The antioxidant effects of alpha lipoic acid offer further support for skin health by protecting against oxidative damage of skin cells from environmental factors.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Gianturco V, Bellomo A, D'Ottavio E, et al. Impact of therapy with alpha-lipoic acid (ALA) on the oxidative stress in the controlled NIDDM: a possible preventive way against the organ dysfunction?. Arch Gerontol Geriatr. 2009;49 Suppl 1:129-133. doi:10.1016\/j.archger.2009.09.022 \u003cbr\u003e\u003cbr\u003e2. Warraich UE, Hussain F, Kayani HUR. Aging - Oxidative stress, antioxidants and computational modeling. Heliyon. 2020;6(5):e04107. Published 2020 May 31. doi:10.1016\/j.heliyon.2020.e04107 \u003cbr\u003e\u003cbr\u003e3. Dos Santos SM, Romeiro CFR, Rodrigues CA, Cerqueira ARL, Monteiro MC. Mitochondrial Dysfunction and Alpha-Lipoic Acid: Beneficial or Harmful in Alzheimer's Disease?. Oxid Med Cell Longev. 2019;2019:8409329. Published 2019 Nov 30. doi:10.1155\/2019\/8409329 \u003cbr\u003e\u003cbr\u003e4. Capece U, Moffa S, Improta I, et al. Alpha-Lipoic Acid and Glucose Metabolism: A Comprehensive Update on Biochemical and Therapeutic Features. Nutrients. 2022;15(1):18. Published 2022 Dec 21. doi:10.3390\/nu15010018 \u003cbr\u003e\u003cbr\u003e5. Jibril AT, Jayedi A, Shab-Bidar S. Efficacy and safety of oral alpha-lipoic acid supplementation for type 2 diabetes management: a systematic review and dose-response meta-analysis of randomized trials. Endocr Connect. 2022;11(10):e220322. Published 2022 Sep 26. doi:10.1530\/EC-22-0322 \u003cbr\u003e\u003cbr\u003e6. Ahmadi M, Keshavarz SA, Abbasi B. Effects of alpha lipoic acid supplementation on serum lipid profile in patients with metabolic syndrome: A randomized, double-blind, placebo-controlled clinical trial. ARYA Atheroscler. 2022;18(4):1-8. doi:10.22122\/arya.2022.26181 \u003cbr\u003e\u003cbr\u003e7. Singh P, Barman B, Thakur MK. Oxidative stress-mediated memory impairment during aging and its therapeutic intervention by natural bioactive compounds. Front Aging Neurosci. 2022;14:944697. Published 2022 Jul 25. doi:10.3389\/fnagi.2022.944697 \u003cbr\u003e\u003cbr\u003e8. Maciejczyk M, Żebrowska E, Nesterowicz M, Żendzian-Piotrowska M, Zalewska A. α-Lipoic Acid Strengthens the Antioxidant Barrier and Reduces Oxidative, Nitrosative, and Glycative Damage, as well as Inhibits Inflammation and Apoptosis in the Hypothalamus but Not in the Cerebral Cortex of Insulin-Resistant Rats. Oxid Med Cell Longev. 2022;2022:7450514. Published 2022 Mar 29. doi:10.1155\/2022\/7450514 \u003cbr\u003e\u003cbr\u003e9. Salehi B, Berkay Yılmaz Y, Antika G, et al. Insights on the Use of α-Lipoic Acid for Therapeutic Purposes. Biomolecules. 2019;9(8):356. Published 2019 Aug 9. doi:10.3390\/biom9080356\u003c\/p\u003e\n\u003c\/details\u003e\n\u003cfooter\u003e\n\u003cul\u003e\n\u003cli\u003eAlpha lipoic acid (ALA) is a naturally occurring compound that functions as a powerful antioxidant in the body.\u003c\/li\u003e\n\u003cli\u003eIt is both water-soluble and fat-soluble, allowing it to work in various cellular environments.\u003c\/li\u003e\n\u003cli\u003eALA is produced in small amounts within the human body and can also be obtained from food sources such as spinach, broccoli, brussels sprouts and organ and red meats.\u003c\/li\u003e\n\u003cli\u003eDue to its antioxidant effects, alpha lipoic acid decreases levels of oxidative stress and reduces symptoms of age-related health decline of the heart, brain, and skin.\u003c\/li\u003e\n\u003cli\u003eStudies show alpha lipoic aids in blood sugar regulation, which is critical for longevity and cellular health.\u003c\/li\u003e\n\u003cli\u003eALA further improves cellular health by supporting ATP production and mitochondrial biogenesis.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/footer\u003e\u003cmain\u003e\n\u003ctable style=\"height: 105.283px;\" width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; width: 99.3437%; height: 20.5333px;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"width: 99.3437%; height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"width: 99.3437%; height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 16.15px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; width: 82.5179%; height: 16.15px;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; width: 16.8258%; height: 16.15px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"width: 54.4153%; height: 17.15px;\" class=\"smalltext\"\u003eAlpha-Lipoic Acid\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; width: 28.1026%; height: 17.15px;\" align=\"right\"\u003e500 mg\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap; width: 16.8258%; height: 17.15px;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"width: 99.3437%; height: 17.15px;\" colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eREV.08.25\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), microcrystalline cellulose, rice flour.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take one (1) capsule 1-2 times per day, preferably with food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/main\u003e\n\u003cdiv class=\"summary\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formulation. \u003c\/strong\u003eProHealth’s alpha lipoic acid was specifically formulated to reduce symptoms of age-related health decline.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEffective dosing: \u003c\/strong\u003eCompared to other brands of alpha lipoic acid on the market containing between 100 – 300 mg of ALA, ProHealth's alpha lipoic acid contains a clinically effective dose of 1,000 mg of alpha lipoic acid per serving, a dose that is supported by the latest scientific studies.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":49221242978464,"sku":"PH644","price":19.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH644_175ML_FRNT_600x600_REV0825-1.png?v=1770129356","url":"https:\/\/wholesale.prohealth.com\/products\/prohealth-alpha-lipoic-acid-1000-mg-30-capsules-ph644","provider":"ProHealth Wholesale","version":"1.0","type":"link"}