{"title":"AMPK Activation","description":"","products":[{"product_id":"prohealth-calcium-akg-longevity-500-mg-60-capsules-ph591","title":"Calcium AKG Longevity - 1,000 mg per serving, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch3\u003eSupport Energy Production, Bone Strength, and Metabolic Function With Age\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy aging processes\u003c\/li\u003e\n\u003cli\u003eSupports heart, bone, and metabolic health\u003c\/li\u003e\n\u003cli\u003eSupports cognitive vitality\u003c\/li\u003e\n\u003cli\u003eHelps to boost antioxidant levels inside cells\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH591_-_COA_Brighton_LOT_2605063_2026.10.21_2.pdf?v=1792700481\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Metabolic Function and Longevity:\u003c\/strong\u003e Alpha-ketoglutarate (AKG) is a compound that is created naturally in the body but tends to diminish with age. In supplement form, AKG can be attached to a calcium salt (Ca-AKG), which has been studied for its role in supporting metabolic function and longevity. (1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eStimulates Autophagy:\u003c\/strong\u003e Autophagy, our internal recycling process that removes dysfunctional cells, decreases with age. Ca-AKG has been found to support this process. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAides in Bone and Muscle Health:\u003c\/strong\u003e Ca-AKG is involved in stimulating protein synthesis and energy production in the body, as it is a vital component of the Krebs cycle - the process that creates ATP (energy) from food. Ca-AKG is also a source of the essential amino acids needed to make collagen, which is a protein that helps to support bone and muscle health. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Blood Sugar Regulation:\u003c\/strong\u003e As we age, our bodies become less efficient at regulating blood sugar. Research shows that Ca-AKG can help to support healthy blood sugar levels. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular Health:\u003c\/strong\u003e The mitochondria, our cells’ main energy hub decreases with age leading to aging and numerous age-related health concerns. Ca-AKG has been found to activate AMPK a pathway that helps maintain cellular energy and support cellular function. (3)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eImproves Antioxidant Levels:\u003c\/strong\u003e Ca-AKG has also been shown to boost cellular antioxidant levels in aged mice, which helped support the mice’s blood vessel elasticity - a measure of good cardiovascular health. (4)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Asadi Shahmirzadi A, Edgar D, Liao CY, et al. Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. Cell Metab. 2020;32(3):447-456.e6. doi:10.1016\/j.cmet.2020.08.004 \u003cbr\u003e\u003cbr\u003e2. Chin R, Fu X, Pai M., et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014;510:397–40. https:\/\/doi.org\/10.1038\/nature13264 \u003cbr\u003e\u003cbr\u003e3. Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D. Alpha-Ketoglutarate: Physiological Functions and Applications. Biomol Ther (Seoul). 2016;24(1):1-8. doi:10.4062\/biomolther.2015.078 \u003cbr\u003e\u003cbr\u003e4. Niemiec T, Sikorska J, Harrison A, et al. Alpha-ketoglutarate stabilizes redox homeostasis and improves arterial elasticity in aged mice. J Physiol Pharmacol. 2011;62(1):37-43. \u003cbr\u003e\u003cbr\u003e5. Demidenko O, Barardo D, Budovskii V, et al. Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test. Aging (Albany NY). 2021;13(22):24485-24499. doi:10.18632\/aging.203736 \u003cbr\u003e\u003cbr\u003e6. Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D. Alpha-Ketoglutarate: Physiological Functions and Applications. Biomol Ther (Seoul). 2016;24(1):1-8. doi:10.4062\/biomolther.2015.078 \u003cbr\u003e\u003cbr\u003e7. Wang Y, Deng P, Liu Y, et al. Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations. Nat Commun. 2020;11(1):5596. Published 2020 Nov 5. doi:10.1038\/s41467-020-19360- \u003cbr\u003e\u003cbr\u003e8. Niemiec T, Sikorska J, Harrison A, et al. Alpha-ketoglutarate stabilizes redox homeostasis and improves arterial elasticity in aged mice. J Physiol Pharmacol. 2011;62(1):37-43. \u003cbr\u003e\u003cbr\u003e9. Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D. Alpha-Ketoglutarate: Physiological Functions and Applications. Biomol Ther (Seoul). 2016;24(1):1-8. doi:10.4062\/biomolther.2015.078 \u003cbr\u003e\u003cbr\u003e10. Asadi Shahmirzadi A, Edgar D, Liao CY, et al. Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. Cell Metab. 2020;32(3):447-456.e6. doi:10.1016\/j.cmet.2020.08.004 \u003cbr\u003e\u003cbr\u003e11. Chin R, Fu X, Pai M., et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014;510:397–40. https:\/\/doi.org\/10.1038\/nature13264\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable style=\"height: 158.733px;\" width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 18.15px;\"\u003e\n\u003ctd style=\"height: 18.15px;\" class=\"smalltext\" colspan=\"3\"\u003eServing Size: 2 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"height: 17.15px;\" class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"font-weight: bold; height: 17.15px;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 17.15px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 34.3px;\"\u003e\n\u003ctd style=\"height: 34.3px;\" class=\"smalltext\"\u003eCalcium\u003cbr\u003e  (as Alpha Ketoglutarate)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 34.3px;\" class=\"smalltext\" align=\"right\"\u003e180 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 34.3px;\" class=\"smalltext\" align=\"right\"\u003e14%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 34.3px;\"\u003e\n\u003ctd style=\"height: 34.3px;\" class=\"smalltext\"\u003eCalcium Alpha Ketoglutarate)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 34.3px;\" class=\"smalltext\" align=\"right\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 34.3px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd style=\"height: 17.15px;\" class=\"smalltext\" colspan=\"3\"\u003e† Daily Value (DV) not established.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.10.25 \u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e Hypromellose (capsule), rice flour.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take two (2) capsules in the morning, with or without food, for daily energy\u003cbr\u003esupport. Or take four (4) capsules 30-60 minutes before exercise for athletic support.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eAlpha-ketoglutarate (AKG) is a compound that is created naturally in the body but tends to diminish with age. In supplement form, AKG can be attached to a calcium salt (Ca-AKG), which has been studied for its role in supporting metabolic function and longevity. \u003csup\u003e6\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eCa-AKG is involved in stimulating protein synthesis and energy production in the body, as it is a vital component of the Krebs cycle - the process that creates ATP (energy) from food. Ca-AKG is also a source of the essential amino acids needed to make collagen, which is a protein that helps to support bone and muscle health.\u003c\/li\u003e\n\u003cli\u003eCa-AKG facilitates our internal recycling process known as autophagy, which removes dysfunctional cells, cell parts and proteins from the body. Autophagy tends to decrease with age, so Ca-AKG may be able to help support this process.\u003c\/li\u003e\n\u003cli\u003eAdding calcium to AKG helps to slow the absorption of AKG allowing it to work longer in the body.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBetter Absorption.\u003c\/strong\u003e Compared to other products that commonly use unbound AKG or AKG bound to arginine, our AKG is bound to calcium. This combination has been shown to promote extended lifespan and health span in mice, even when administered late in life. It also helps to slow the absorption allowing it to work longer in the body.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eResearch-Supported.\u003c\/strong\u003e Calcium AKG Longevity is formulated using 1,000 mg of calcium alpha ketoglutarate, which has been shown in clinical research to promote longevity by reversing biological age (measured by biological age tests), improve markers of heart health and decrease risk of age-related decline in bone health.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":42860943016096,"sku":"PH591","price":25.25,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH591_FRNT_175ML_600x600_d69eba00-2fa4-413d-b522-4349d16052df.png?v=1770390977"},{"product_id":"prohealth-pure-trans-resveratrol-powder-1000-mg-30-grams-ph576","title":"Pure Trans-Resveratrol Powder - 30 grams","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\n\u003ch2\u003eSupports brain, cardiovascular, cellular and joint health\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports brain health and cognitive function \u003c\/li\u003e\n\u003cli\u003eSupports cellular and DNA health \u003c\/li\u003e\n\u003cli\u003eSupports healthy aging \u003c\/li\u003e\n\u003cli\u003eSupports heart and metabolic health \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH576_-_COA_Brighton_LOT_26387_2026.07.20_2.pdf?v=1792705748\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Brain Health.\u003c\/strong\u003e Research shows that resveratrol, a molecule found in red grapes and wine, may protect the brain from symptoms of brain aging, including improving memory and delaying cognitive decline. The neuroprotective effects of resveratrol come from its sirtuin-activating, inflammation-regulating, mitochondrial-supporting and antioxidant activity.\u003csup\u003e1-3\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular and DNA Health.\u003c\/strong\u003e Resveratrol acts as a potent antioxidant, which reduces harmful oxidative stress. It also activates genes called sirtuins. Healthy sirtuin activity helps to fight cellular senescence, support DNA repair, boost mitochondrial function and generate cellular energy through ATP production.\u003csup\u003e3,4\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Healthy Aging.\u003c\/strong\u003e Resveratrol activates SIRT1, often referred to as the \"longevity gene.\" Healthy older adults tend to have higher levels of SIRT1 activity, and SIRT1 overexpression can increase lifespan in worms and animals. In humans, SIRT1 supports healthy aging and longevity.\u003csup\u003e5,6\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Joint Health.\u003c\/strong\u003e Due to its role in supporting healthier inflammatory responses and modulating oxidative stress, resveratrol has exhibited joint-protective effects.\u003csup\u003e7 \u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Heart Health.\u003c\/strong\u003e Resveratrol is well-known for its link to supporting cardiovascular health. Research has found that resveratrol benefits endothelial function, blood vessel health and blood pressure by boosting SIRT1 activity, reducing oxidative stress and increasing nitric oxide production.\u003csup\u003e8,9\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Metabolic Health.\u003c\/strong\u003e Resveratrol activates SIRT1, which has been studied for its role in supporting healthier glucose metabolism. People with reduced SIRT1 expression tend to have higher blood sugar, poor glucose control and metabolic disorders.\u003csup\u003e10\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Salehi B, Mishra AP, Nigam M, et al. Resveratrol: A Double-Edged Sword in Health Benefits. Biomedicines. 2018;6(3):91. Published 2018 Sep 9.\u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6164842\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.3390\/biomedicines6030091 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e2. Bastianetto S, Ménard C, Quirion R. Neuroprotective action of resveratrol. Biochim Biophys Acta. 2015;1852(6):1195-1201. doi:10.1016\/j.bbadis.2014.09.011 \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/25281824\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.1016\/j.bbadis.2014.09.011 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e3. Moraes DS, Moreira DC, Andrade JMO, Santos SHS. Sirtuins, brain and cognition: A review of resveratrol effects. IBRO Rep. 2020;9:46-51. Published 2020 Jun 26. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7733131\/?report=reader\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.1016\/j.ibror.2020.06.004 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e4. Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem. 2005;280(17):17187-17195. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15749705\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.1074\/jbc.M501250200 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e5. Kilic U, Gok O, Erenberk U, et al. A remarkable age-related increase in SIRT1 protein expression against oxidative stress in elderly: SIRT1 gene variants and longevity in human. PLoS One. 2015;10(3):e0117954. Published 2015 Mar 18. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4365019\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.1371\/journal.pone.0117954 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e6. Salminen A, Kaarniranta K. SIRT1: regulation of longevity via autophagy. Cell Signal. 2009;21(9):1356-1360. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19249351\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.1016\/j.cellsig.2009.02.014 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e7. Nguyen C, Savouret JF, Widerak M, Corvol MT, Rannou F. Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review. Nutrients. 2017;9(1):45. Published 2017 Jan 6. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC5295089\/?report=classic\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.3390\/nu9010045 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e8. Marques BCAA, Trindade M, Aquino JCF, et al. Beneficial effects of acute trans-resveratrol supplementation in treated hypertensive patients with endothelial dysfunction. Clin Exp Hypertens. 2018;40(3):218-223. \u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/29431520\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.1080\/10641963.2017.1288741 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e9. Bonnefont-Rousselot D. Resveratrol and Cardiovascular Diseases. Nutrients. 2016;8(5):250. Published 2016 May 2. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4882663\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.3390\/ijms20030535 \u003c\/a\u003e\u003cbr\u003e\u003cbr\u003eHou CY, Tain YL, Yu HR, Huang LT. The Effects of Resveratrol in the Treatment of Metabolic Syndrome. Int J Mol Sci. 2019;20(3):535. Published 2019 Jan 28. \u003ca href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6387422\/\" style=\"color: #0000ff;\" target=\"_blank\"\u003edoi:10.3390\/ijms20030535 \u003c\/a\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eResveratrol is a naturally occurring polyphenol that works by activating longevity genes called sirtuins, acting as an antioxidant, regulating inflammatory responses and supporting mitochondrial health.  \u003c\/li\u003e\n\u003cli\u003eTrans-resveratrol is the most bioavailable form of resveratrol.  \u003c\/li\u003e\n\u003cli\u003eProHealth's Micronized Trans-Resveratrol powder delivers 1000 mg of pharmaceutical grade, 98% pure, natural trans-resveratrol per serving. \u003c\/li\u003e\n\u003cli\u003eThe particles are micronized to provide superior absorption. \u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\" colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Scoop\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 30\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap;\" class=\"smalltext\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eVeri-te® Pure \u003cem\u003eTrans\u003c\/em\u003e-Resveratrol\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.01.25 \u003cbr\u003e\u003cbr\u003eVeri-te® is a registered trademark of the Lallemand group.\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake one (1) scoop daily with food, or as directed by your\u003cbr\u003ehealthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place. Protect from light, heat and humidity. Do not use if tamper-evident packaging is broken. Package filled by weight, not volume.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cem\u003eThis product is sold by weight, not volume. Contents may settle during shipping and handling. Each leveled scoop contains approximately 1,000 mg. A milligram scale is recommended for an exact dose.\u003c\/em\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cp\u003e\u003cstrong\u003eBest Form of Resveratrol.\u003c\/strong\u003e Other resveratrol supplements are typically composed of 50% trans-resveratrol and 50% cis-resveratrol. ProHealth uses trans-resveratrol because it has a higher biological availability.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSuperior Absorption.\u003c\/strong\u003e The particles are micronized to provide superior absorption and the 100 gram container is perfect for people wanting to buy in bulk.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eNatural Source.\u003c\/strong\u003e ProHealth’s trans-resveratrol is pure and natural for the highest quality.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eHigher Dose.\u003c\/strong\u003e Each serving contains 1000 mg pure and natural trans-resveratrol.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eAdditional Certifications.\u003c\/strong\u003e Non-GMO, Vegan and Gluten-Free\u003c\/p\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":42864174858400,"sku":"PH576","price":35.1,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH576_FRNT_120ML_Jar-600x600_REV1026.png?v=1791991774"},{"product_id":"prohealth-nmn-pro-complete-1000-mg-75-grams-ph578","title":"NMN Pro™ Complete - Uthever® NMN, Trans-Resveratrol, TMG - 75 grams","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eHelps combat aging, improves heart health and promotes muscle strength\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eNMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.\u003c\/li\u003e\n\u003cli\u003eNicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.\u003c\/li\u003e\n\u003cli\u003eTrans-Resveratrol boosts the effectiveness of NMN, supports healthy aging, and promotes a balanced immune response.\u003c\/li\u003e\n\u003cli\u003eTMG is a methyl donor that complements NMN supplementation by helping replenish the body's methyl pool.\u003c\/li\u003e\n\u003cli\u003eNMN Pro Complete is the first and only perfectly balanced combination of NMN, Trans-Resveratrol and TMG on the market. Instead of having to take three separate supplements each day, you can now get the ideal balance of all three in one convenient serving.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH578-COA-2025-12-16_Shopify.jpg?v=1767825863\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cbr\u003e\n\u003ch3\u003eResearch Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003e Supports Longevity.\u003c\/strong\u003e Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies. (1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtects Heart and Muscle Health.\u003c\/strong\u003e Studies have shown that the combination of NMN and resveratrol is uniquely able to increase NAD+ concentrations even more than NMN alone. In heart tissue, NAD+ concentrations were shown to be 1.6 times greater, and in skeletal muscle, NAD+ concentrations were 1.7 times greater than when supplementing only with NMN. (13)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e Blood Sugar Regulation.\u003c\/strong\u003e As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e Supports Metabolism and Healthy Weight.\u003c\/strong\u003e Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight. (3,4,5)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e Supports Healthy Cognition:\u003c\/strong\u003e Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction. (6,7)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003e Supports Healthy Skin:\u003c\/strong\u003e In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. (8,9)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016\/j.cmet.2016.09.004 \u003cbr\u003e\u003cbr\u003e2. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016\/j.bbadis.2021.166287 \u003cbr\u003e\u003cbr\u003e3. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080\/08982104.2020.1820521 \u003cbr\u003e\u003cbr\u003e4. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1\/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016\/j.jphotobiol.2021.112238 \u003cbr\u003e\u003cbr\u003e5. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390\/nu14040755 \u003cbr\u003e\u003cbr\u003e6. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007\/s11357-020-00165-5 \u003cbr\u003e\u003cbr\u003e7. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186\/s12970-021-00442- \u003cbr\u003e\u003cbr\u003e8. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016\/j.cmet.2016.09.013 \u003cbr\u003e\u003cbr\u003e9. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016\/j.redox.2019.101192 \u003cbr\u003e\u003cbr\u003e10. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016\/j.brainres.2016.04.060 \u003cbr\u003e\u003cbr\u003e11. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016\/j.cmet.2011.08.014 \u003cbr\u003e\u003cbr\u003e12. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126\/science.abe9985 \u003cbr\u003e\u003cbr\u003e13. Bai L, Yau L, Tong T, Chan W, Zhang W, Jiang Z. Improvement of tissue‐specific distribution and biotransformation potential of nicotinamide mononucleotide in combination with ginsenosides or resveratrol. Pharmacol Res Perspect. 2022;10(4):e00986. doi:10.1002\/prp2.986\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eNicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient. NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, brain health, heart health, body weight and gene expression.\u003c\/li\u003e\n\u003cli\u003eNMN and trans-resveratrol work synergistically, which is why longevity experts recommend taking them together for the greatest effectiveness. This dynamic duo has been likened to the operation of a car, with NMN as the fuel and trans-resveratrol as the accelerator pedal.\u003c\/li\u003e\n\u003cli\u003eRegular resveratrol is composed of 50% trans-resveratrol and 50% cis-resveratrol. Because research suggests that only the trans-form has valuable biological activity, NMN Pro Complete contains pure, natural, pharmaceutical grade trans-resveratrol.\u003c\/li\u003e\n\u003cli\u003eTMG, also known as betaine anhydrous, is an amino acid that supports the body's methylation processes. These processes are known to decline with age and may also be affected by common gene mutations. Also, NMN supplementation may require the use of methyl groups to help facilitate the conversion of NAD+ in your cells, thereby activating sirtuin genes and promoting longevity.*\u003c\/li\u003e\n\u003cli\u003eMany top anti-aging experts suggest that safeguarding against methyl depletion may be a wise proactive step to augment your NMN intake. TMG, the choice of many of those experts, is an excellent way to help support your body's ability to maintain an adequate methyl pool.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnly Clincially-Proven NMN.\u003c\/strong\u003e ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formula.\u003c\/strong\u003e NMN Pro Complete is the first and only perfectly balanced combination of NMN, Trans-Resveratrol and TMG on the market. Instead of having to take three separate supplements each day, you can now get the ideal balance of all three in one convenient serving. A single scoop of NMN Pro Complete will provide you with 1,000 mg of NMN, 1,000 mg of trans-resveratrol, and 500 mg of TMG – the daily dosage most often recommended by the world's leading longevity experts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMicronized.\u003c\/strong\u003e Micronized for superior absorption and bioavailability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolvent-Free.\u003c\/strong\u003e Compared to other NMN products, ours is made without any chemical solvents.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong\u003eBe Aware of Fake NMN:\u003c\/strong\u003e Fraudulent companies are always attempting to out-price competitors by using NMN fake ingredients to gain market share, which is not fair to you, the consumer, or the reputable companies, like ProHealth that spends time and resources to ensure a safe and pure NMN product.\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 1 Scoop (2.5 g)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eUthever® β-Nicotinamide Mononucleotide (NMN)\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eVeri-te® Trans-Resveratrol\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eTrimethylglycine (TMG)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e500 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.09.25\u003cbr\u003e\u003cbr\u003eUthever® is a registered trademark of Effepharm (Shanghai) Co., Ltd. Veri-te® is a registered *These statements have not been evaluated by the Food trademark of the Lallemand group.\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eNone.\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Add one (1) scoop to 8-12 oz of liquid per day, mix thoroughly and drink, preferably in the morning.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":42864416981152,"sku":"PH578","price":82.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH578_FRNT_250ML_Jar_600x600_REV0925.png?v=1775506129"},{"product_id":"prohealth-longevity-berberine-pro-600-mg-60-capsules-ph613","title":"Berberine Pro - 600 mg, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eCombat Aging, Support Glucose Metabolism and Promote Healthy Immune Function\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports healthy aging by activating AMPK\u003c\/li\u003e\n\u003cli\u003eImproves body composition\u003c\/li\u003e\n\u003cli\u003eEnhances heart health\u003c\/li\u003e\n\u003cli\u003eAids in blood sugar management\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH613_-_Qalitex_COA_LOT_2510149_2025-11-14.pdf?v=1764198150\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003ePromotes Longevity\u003c\/strong\u003e. Berberine has been shown to activate AMPK, which is known as the metabolic master switch and has been shown to extend lifespan in animal species when activated. (1)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e Enhances Heart Health\u003c\/strong\u003e. Research shows that berberine supports several markers of heart health. (2)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Healthy Blood Sugar\u003c\/strong\u003e. Studies show that berberine supports healthy fasting blood sugar levels and fasting insulin levels. (3) Many people find that by improving blood sugar regulation, they experience notable berberine weight loss benefits, as it aids in managing metabolism and curbing excessive cravings.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Stancu AL. AMPK activation can delay aging. Discoveries (Craiova). 2015;3(4):e53. Published 2015 Dec 31. doi:10.15190\/d.2015.45 \u003cbr\u003e\u003cbr\u003e2. Koppen LM, Whitaker A, Rosene A, Beckett RD. Efficacy of Berberine Alone and in Combination for the Treatment of Hyperlipidemia: A Systematic Review. J Evid Based Complementary Altern Med. 2017;22(4):956-968. doi:10.1177\/2156587216687695 \u003cbr\u003e\u003cbr\u003e3. Yin J, Xing H, Ye J. Efficacy of berberine in patients with type 2 diabetes mellitus. Metabolism. 2008;57(5):712-717. doi:10.1016\/j.metabol.2008.01.013 \u003cbr\u003e\u003cbr\u003e4. Baziar N, Nasli-Esfahani E, Djafarian K, et al. The Beneficial Effects of Alpha Lipoic Acid Supplementation on Lp-PLA2 Mass and Its Distribution between HDL and apoB-Containing Lipoproteins in Type 2 Diabetic Patients: A Randomized, Double-Blind, Placebo-Controlled Trial. Oxid Med Cell Longev. 2020;2020:5850865. Published 2020 Mar 9. doi:10.1155\/2020\/5850865\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd style=\"font-weight: bold;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eChromium\u003cbr\u003e (as Chromium Picolinate)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e200 mcg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e571%\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eBerberine HCl (from \u003cem\u003eBerberis\u003c\/em\u003e \u003cbr\u003e  \u003cem\u003earistata\u003c\/em\u003e Bark Extract)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e600 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eBioPerine® Black Pepper Fruit\u003cbr\u003e  Extract (95% Piperine)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e3.4 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cp\u003eRev. 09.25\u003c\/p\u003e\nBioPerine® is a registered trademark of Sabinsa, Co.\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), rice flour.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake one (1) capsule 2-3 times per day with food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eHimalayan Berberine promotes longevity by activating the AMPK pathway which senses each cell's energy status and triggers responses that help to maintain the cell's energy at its optimum level. By stimulating mitochondrial biogenesis, berberine activates genes similar to those typically turned on by exercise.\u003c\/li\u003e\n\u003cli\u003eBoth animal and human studies have demonstrated berberine's ability to support glucose metabolism and help maintain healthy blood sugar levels in those who are already in the normal range. Because it helps to manage blood sugar, many people choose berberine for weight loss support.\u003c\/li\u003e\n\u003cli\u003e50mg of Alpha Lipoic Acid is added to further support the blood sugar regulating and heart health promoting effects of this berberine supplement.\u003c\/li\u003e\n\u003cli\u003e10 mg of Bioperine® Black Pepper Fruit Extract is incorporated to boost absorption and improve the efficacy of bioavailable berberine.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cp\u003e\u003cstrong\u003e Unique Formulation.\u003c\/strong\u003e Berberine Lifespan Pro by ProHealth Longevity is formulated using clinically effective doses of Berberine along with the potent antioxidant Alpha Lipoic Acid which has been shown to support heart health.4 Additionally ProHealth Longevity’s Berberine Pro Longevity includes Bioperine®, which enhances absorption of berberine to maximize efficacy. Other berberine supplements do not include these supporting ingredients and therefore may not be as effective.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBetter Absorption.\u003c\/strong\u003e The addition of Bioperine® enhances the absorption of berberine for maximum efficacy.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eFree of Unwanted Fillers or By-Products.\u003c\/strong\u003e Berberine is free of dairy, egg, soy, fish, gluten, wheat, artificial preservatives and chemicals.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/p\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":45096766800032,"sku":"PH613","price":29.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH613_175CC_FRNT_600x600-REV0925.png?v=1764688118"},{"product_id":"prohealth-trans-resveratrol-1000-mg-60-capsules-ph528","title":"Trans-Resveratrol Plus - 1000 mg per serving, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eSupports Brain, Cardiovascular and Joint Health\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports brain health and cognitive function\u003c\/li\u003e\n\u003cli\u003eSupports cellular and DNA health\u003c\/li\u003e\n\u003cli\u003eSupports healthy aging\u003c\/li\u003e\n\u003cli\u003eSupports heart and metabolic health\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH528-_COA_Brighton_LOT_23192_2024-10-30_1.pdf?v=1733499816\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e Supports Brain Health\u003c\/strong\u003e. Research shows that resveratrol, a molecule found in red grapes and wine, may protect the brain from symptoms of brain aging, including improving memory and delaying cognitive decline. The neuroprotective effects of resveratrol come from its sirtuin-activating, inflammation-regulating, mitochondrial-supporting and antioxidant activity. (1-3)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Cellular and DNA Health\u003c\/strong\u003e. Resveratrol acts as a potent antioxidant, which reduces harmful oxidative stress. It also activates genes called sirtuins. Healthy sirtuin activity helps to fight cellular senescence, support DNA repair, boost mitochondrial function and generate cellular energy through ATP production. (3,4)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Healthy Aging\u003c\/strong\u003e. Resveratrol activates SIRT1, often referred to as the \"longevity gene.\" Healthy older adults tend to have higher levels of SIRT1 activity, and SIRT1 overexpression can increase lifespan in worms and animals. In humans, SIRT1 supports healthy aging and longevity. (5,6)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Joint Health\u003c\/strong\u003e. Due to its role in supporting healthier inflammatory responses and modulating oxidative stress, resveratrol has exhibited joint-protective effects. (7)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Heart Health\u003c\/strong\u003e. Resveratrol is well-known for its link to supporting cardiovascular health. Research has found that resveratrol benefits endothelial function, blood vessel health and blood pressure by boosting SIRT1 activity, reducing oxidative stress and increasing nitric oxide production. (8,9)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSupports Metabolic Health\u003c\/strong\u003e. Resveratrol activates SIRT1, which has been studied for its role in supporting healthier glucose metabolism. People with reduced SIRT1 expression tend to have higher blood sugar, poor glucose control and metabolic disorders. (10)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Salehi B, Mishra AP, Nigam M, et al. Resveratrol: A Double-Edged Sword in Health Benefits. Biomedicines. 2018;6(3):91. Published 2018 Sep 9. doi:10.3390\/biomedicines6030091 \u003cbr\u003e\u003cbr\u003e2. Bastianetto S, Ménard C, Quirion R. Neuroprotective action of resveratrol. Biochim Biophys Acta. 2015;1852(6):1195-1201. doi:10.1016\/j.bbadis.2014.09.011 \u003cbr\u003e\u003cbr\u003e3. Moraes DS, Moreira DC, Andrade JMO, Santos SHS. Sirtuins, brain and cognition: A review of resveratrol effects. IBRO Rep. 2020;9:46-51. Published 2020 Jun 26. doi:10.1016\/j.ibror.2020.06.004 \u003cbr\u003e\u003cbr\u003e4. Borra MT, Smith BC, Denu JM. Mechanism of human SIRT1 activation by resveratrol. J Biol Chem. 2005;280(17):17187-17195. doi:10.1074\/jbc.M501250200 \u003cbr\u003e\u003cbr\u003e5. Kilic U, Gok O, Erenberk U, et al. A remarkable age-related increase in SIRT1 protein expression against oxidative stress in elderly: SIRT1 gene variants and longevity in human. PLoS One. 2015;10(3):e0117954. Published 2015 Mar 18. \u003cbr\u003e\u003cbr\u003e6. Salminen A, Kaarniranta K. SIRT1: regulation of longevity via autophagy. Cell Signal. 2009;21(9):1356-1360. doi:10.1016\/j.cellsig.2009.02.014 \u003cbr\u003e\u003cbr\u003e7. Nguyen C, Savouret JF, Widerak M, Corvol MT, Rannou F. Resveratrol, Potential Therapeutic Interest in Joint Disorders: A Critical Narrative Review. Nutrients. 2017;9(1):45. Published 2017 Jan 6. doi:10.3390\/nu9010045 \u003cbr\u003e\u003cbr\u003e8. Marques BCAA, Trindade M, Aquino JCF, et al. Beneficial effects of acute trans-resveratrol supplementation in treated hypertensive patients with endothelial dysfunction. Clin Exp Hypertens. 2018;40(3):218-223. doi:10.1080\/10641963.2017.1288741 \u003cbr\u003e\u003cbr\u003e9. Bonnefont-Rousselot D. Resveratrol and Cardiovascular Diseases. Nutrients. 2016;8(5):250. Published 2016 May 2. doi:10.3390\/nu8050250 \u003cbr\u003e\u003cbr\u003e10. Hou CY, Tain YL, Yu HR, Huang LT. The Effects of Resveratrol in the Treatment of Metabolic Syndrome. Int J Mol Sci. 2019;20(3):535. Published 2019 Jan 28. doi:10.3390\/ijms20030535\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eBest Form of Resveratrol.\u003c\/strong\u003e Other resveratrol supplements are typically composed of 50% trans-resveratrol and 50% cis-resveratrol. ProHealth uses trans-resveratrol because it has a higher biological availability.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNatural Source.\u003c\/strong\u003e ProHealth’s trans-resveratrol is pure and natural for the highest quality.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eHigher Dose.\u003c\/strong\u003e Each serving contains 1000 mg pure and natural trans-resveratrol.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formulation.\u003c\/strong\u003e Compared to other products, ProHealth Longevity’s Trans-Resveratrol also includes 420 mg of a proprietary blend of quercetin, organic red wine extract, organic decaf green tea extract and BioPerine® to support absorption. These select co-factors and BioPerine® included in this formula can improve absorption and increase C-max blood levels by up to 1544% compared to regular resveratrol supplements.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAdditional Certifications.\u003c\/strong\u003e Non-GMO, Vegan and Gluten-Free\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\" style=\"height: 174.883px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth align=\"left\" colspan=\"3\" style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003eServing Size: 2 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold; height: 17.15px;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 17.15px;\"\u003ePure  Veri-te® Trans-Resveratrol\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 17.15px;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 68.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 68.6px;\"\u003e\n\u003cstrong\u003eProprietary Blend\u003c\/strong\u003e\u003cbr\u003eQuercetin Dihydrate (from \u003cem\u003eSophora japonica\u003c\/em\u003e Flower Extract), Red Wine (\u003cem\u003eVitis vinifera\u003c\/em\u003e) Fruit Extract, Green Tea Leaf Extract, BioPerine® Black Pepper Fruit Extract (95% Piperine)®\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 68.6px;\"\u003e420 mg\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 68.6px;\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 17.15px;\"\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\" style=\"height: 17.15px;\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.08.25\u003cbr\u003eVeri-te® is a registered trademark of the Lallemand group. BioPerine® is a registered trademark of Sabinsa, Co.\u003cbr\u003e\u003cbr\u003e** Herbal products such as this are likely to have minor color variation from batch to batch because of the geographical and seasonal variations of the raw material.\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), rice flour.\u003cstrong\u003e\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake two (2) capsules per day, with food, preferably in the morning.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNOTE:\u003c\/strong\u003e Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":45096814117024,"sku":"PH528","price":31.08,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH528_175CC_FRNT_600x600-REV0825-1.png?v=1770653310"},{"product_id":"prohealth-optimized-curcumin-longvida-500-mg-60-capsules-ph403","title":"Optimized Curcumin Longvida® - 500 mg, 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eSupports Cognition, Memory \u0026amp; Overall Health\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports a healthy inflammatory response\u003c\/li\u003e\n\u003cli\u003ePromotes joint health and flexibility\u003c\/li\u003e\n\u003cli\u003eLongvida is 285 times more bioavailable than regular curcumin\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH403_-_COA_Brighton__LOT_26034_2025-11-17_2.pdf?v=1764369411\" target=\"_blank\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\"\u003eView Certificate of Analysis  \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" style=\"width: 100%;\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth align=\"left\" colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 2 Capsules\u003cbr\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" style=\"font-weight: bold;\" class=\"smalltext\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap;\" class=\"smalltext\"\u003e%DV\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eLongvida® Optimized Curcumin Extract\u003cbr\u003e  (from \u003cem\u003eCurcuma longa\u003c\/em\u003e [Turmeric] root)\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap;\" class=\"smalltext\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap;\" class=\"smalltext\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.01.25\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e Stearic acid, maltodextrin, ascorbyl palmitate (Vitamin C), silicon dioxide, vegetable capsule.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCONTAINS:\u003c\/strong\u003e Soy (as soy lecithin, a component of Longvida®)\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take two (2) capsules per day, or as recommended by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e Do not take turmeric if you have a biliary tract obstruction or are taking a steroidal anti-inflammatory such as prednisone. For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cem\u003eLONGIVIDA® extract is patented under US 9192644 \u0026amp; EP 1993365 (other patents pending and LONGVIDA® is a registered trademark of Verdure Sciences Inc.\u003c\/em\u003e\n\u003cp\u003e \u003c\/p\u003e\n\u003cp\u003eOptimized Curcumin Longvida® by ProHealth is a finely-tuned matrix of ingredients brought together in a gentle multi-step process. The end product is precisely set in a way that preserves and protects the curcumin from the harsh environment of the stomach, dissolves at the point of absorption in the GI tract, and helps the free form of curcumin cross into the blood stream and target tissues.*\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003ch2\u003eAbout Longvida®\u003c\/h2\u003e\n\u003col\u003e\n\u003cli\u003eMore than a \u003cem\u003edozen research studies and clinical trials\u003c\/em\u003e(1) in independent labs have been completed on Longvida.\u003c\/li\u003e\n\u003cli\u003eOne small, single daily dose of Longvida offered \u003cstrong\u003esignificant health benefits in just 30 days.\u003c\/strong\u003e\n\u003c\/li\u003e\n\u003cli\u003ePublished chronic-dosing safety studies on Longvida support a strong safety profile.\u003c\/li\u003e\n\u003cli\u003eLongvida is 285 times more bioavailable than regular curcumin.\u003c\/li\u003e\n\u003cli\u003eLongvida offers therapeutic levels of free (not deactivated\/metabolized) curcumin.\u003c\/li\u003e\n\u003cli\u003ePromotes joint health and flexibility\u003c\/li\u003e\n\u003cli\u003eMaintain a healthy inflammatory response already in the healthy range\u003c\/li\u003e\n\u003cli\u003eCurcumin from Longvida passes the blood-brain barrier.\u003c\/li\u003e\n\u003cli\u003eLongvida contains no metabolic inhibitors, volatile oils, or crude, unpurified ingredients.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003ch2\u003e\n\u003cstrong\u003eAbout SLCP™ Technology\u003c\/strong\u003e\n\u003c\/h2\u003e\n\u003cp\u003eCutting-edge SLCP™ Technology (patent pending) is responsible for the 'magic' of Longvida® SLCP is the ideal absorption-promoting system, based on real, live research data that was repeated over and over using validated analytical methodologies. Yet all the ingredients are generally recognized as safe (GRAS) food additives, and Longvida® is free of harsh solvents or volatile oils.\u003c\/p\u003e\n\u003ch2\u003eGlyphosate Residue Free\u003c\/h2\u003e\n\u003cp\u003eCertified by a third party ISO 17025 accredited laboratory to be free of glyphosate residue.\u003c\/p\u003e\n\u003cp\u003eReferences:\u003c\/p\u003e\n\u003cp\u003eDiverse effects of a low-dose supplement of lipidated curcumin (as Longvida) in healthy middle-aged people. Disilvestro et al. Nutr. J. 2012 26;11:79 doi 10.1186\/1475-2891-11-79\u003c\/p\u003e\n\u003cp\u003eEffects of Longvida on soluble tau oligomers and cognitive and synaptic deficits. Frautschy et al. AAIC 2011, Paris France.\u003c\/p\u003e\n\u003cp\u003eHuman pharmacokinetics of chronic dosing of Longvida: Dose-concentration correlation. UCLA, 2011.\u003c\/p\u003e\n\u003cp\u003eAcute human pharmacokinetics of 40mg curcumin (as Longvida®) leads to therapeutic blood levels. Shah et al. Planta Med 2012; 78-PH5\u003c\/p\u003e\n\u003cp\u003eEfficacy of Longvida in Stage III human trials, TATA Memorial Centre, Mumbai. Study ongoing.\u003c\/p\u003e\n\u003cp\u003eCurcumin suppresses soluble tau oligomers and corrects molecular chaperone, synaptic and behavioral deficits in aged human tau transgenic mice. Ma et al 2012. Journal of Biological Chemistry.\u003c\/p\u003e\n\u003cp\u003eDoes Longvida® provide an alternative to diltiazem for lowering mucopolysaccharide levels in Sanfillippo syndrome? A human case study. Taylor 2010.\u003c\/p\u003e\n\u003cp\u003eEffects of Longvida® in Trisomy 21: Human Case Studies. Fish, 2010\u003c\/p\u003e\n\u003cp\u003eAnti-inflammatory effects of Longvida® compared to unformulated curcumin. University of Rhode Island, 2011. Manuscript in development\u003c\/p\u003e\n\u003cp\u003eExpression of GFAP in p25 model after dosing of Longvida®. National University of Singapore, 2011.\u003c\/p\u003e\n\u003cp\u003eAcute human bioavailability of Longvida®: 65x Greater Bioavailability: 65x Greater Bioavailability. Gota et al. J Ag Food Chem 2010 58(4): 2095-2099\\\u003c\/p\u003e\n\u003cp\u003eCurcumin bioavailability, activity and mechanism for cognitive health using Longvida®. Begum et al. J Pharmacol Exp Ther. 2008 Jul;326(1):196-208\u003c\/p\u003e\n\u003cp\u003eBioavailability, brain concentrations, activity and dose-response of Longvida® SLCP. Frautschy, SA. 38th Annual Meeting of the Society of Neuroscience , Washington DC, November 15, 2008.\u003c\/p\u003e\n\u003cp\u003eLongvida® synergizes with Omega-3 fatty acids: effects on cognitive mechanisms. Frautschy, SA et al. 39th Annual Meeting of the Society of Neuroscience , Chicago, IL October 2009.\u003c\/p\u003e\n\u003cp\u003eEfficacy of Longvida® in relation to systemic availability in the brain. Frautschy, SA et al. 39th Annual Meeting of the Society of Neuroscience , Chicago, IL October 2009.\u003c\/p\u003e\n\u003cp\u003eChronic dosing safety assessment of a Solid Lipid Curcumin Particle (Longvida) formulation. Dadhaniya et al. Food Chem Toxicol. 2011 Aug; 49(8):1834-42.\u003c\/p\u003e\n\u003cspan style=\"color: #666666; font-size: 8pt;\"\u003e*These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/span\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":45096843411616,"sku":"PH403","price":31.49,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH403_175ML_FRNT_600x600_67a6cdcd-232f-42a0-81ee-e615846c04af.png?v=1772208711"},{"product_id":"prohealth-nmn-pro-complete-capsules-120-capsules-ph633","title":"ProHealth Longevity NMN Pro™ Complete Capsules - 120 Capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003ch2\u003eA Perfectly Balanced Combination of NMN, Trans-Resveratrol and TMG\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eNMN supplementation has been found to support various parameters of health, including physical endurance and muscle strength, neurological function, heart health, blood sugar management, body weight, and gene expression.\u003c\/li\u003e\n\u003cli\u003eNicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.\u003c\/li\u003e\n\u003cli\u003eNMN Pro Complete is the first and only perfectly balanced combination of NMN, Trans-Resveratrol, and TMG on the market. Instead of having to take three separate supplements each day, you can now get the ideal balance of all three in a convenient capsule serving.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH633_-_COA_Brighton_LOT_26445_2026.08.11_2.pdf?v=1792087544\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Longevity.\u003c\/strong\u003e Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies. (1)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eBlood Sugar Regulation.\u003c\/strong\u003e As we age, we have more trouble processing glucose, leading to higher blood sugar—a known contributor to several metabolic-related disorders. Supplemental NMN has been shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Metabolism and Healthy Weight.\u003c\/strong\u003e Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight. (3,4,5)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Healthy Cognition:\u003c\/strong\u003e Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction. (6,7,8,9)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Healthy Skin:\u003c\/strong\u003e In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. (10,11)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016\/j.cmet.2016.09.004 \u003cbr\u003e\u003cbr\u003e2. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126\/science.abe9985 \u003cbr\u003e\u003cbr\u003e3. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390\/nu14040755 \u003cbr\u003e\u003cbr\u003e4. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186\/s12970-021-00442- \u003cbr\u003e\u003cbr\u003e5. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016\/j.cmet.2011.08.014 \u003cbr\u003e\u003cbr\u003e6. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016\/j.cmet.2016.09.013 \u003cbr\u003e\u003cbr\u003e7. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016\/j.redox.2019.101192 \u003cbr\u003e\u003cbr\u003e8. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007\/s11357-020-00165-5 \u003cbr\u003e\u003cbr\u003e9. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016\/j.brainres.2016.04.060 \u003cbr\u003e\u003cbr\u003e10. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1\/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016\/j.jphotobiol.2021.112238 \u003cbr\u003e\u003cbr\u003e11. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016\/j.bbadis.2021.166287\u003c\/p\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eNicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient. NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, brain health, heart health, body weight and gene expression.\u003c\/li\u003e\n\u003cli\u003eNMN and trans-resveratrol work synergistically, which is why longevity experts recommend taking them together for the greatest effectiveness. This dynamic duo has been likened to the operation of a car, with NMN as the fuel and trans-resveratrol as the accelerator pedal.\u003c\/li\u003e\n\u003cli\u003eRegular resveratrol is composed of 50% trans-resveratrol and 50% cis-resveratrol. Because research suggests that only the trans form has valuable biological activity, NMN Pro Complete contains pure, natural, pharmaceutical grade trans-resveratrol to maximize its effectiveness.\u003c\/li\u003e\n\u003cli\u003eTMG, also known as betaine anhydrous, is an amino acid that supports the body's methylation processes. These processes are known to decline with age and may also be affected by common gene mutations. Also, NMN supplementation may require the use of methyl groups to help facilitate the conversion of NAD+ in your cells, thereby activating sirtuin genes and promoting longevity.*\u003c\/li\u003e\n\u003cli\u003eMany top anti-aging experts suggest that safeguarding against methyl depletion may be a wise proactive step to augment your NMN intake. TMG, the choice of many of those experts, is an excellent way to help support your body's ability to maintain an adequate methyl pool.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 4 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eUthever® β-Nicotinamide Mononucleotide (NMN)\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eVeri-te® Pure trans-Resveratrol)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eTrimethylglycine (TMG)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e500 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.09.25\u003cbr\u003e\u003cbr\u003eUthever® is a registered trademark of Effepharm (Shanghai) Co., Ltd. Veri-te® is a registered trademark of the Lallemand group.\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS:\u003c\/strong\u003e Hypromellose (capsule), microcrystalline cellulose.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take four (4) capsules per day, with or without food, preferably in the morning.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOnly Clincially-Proven NMN.\u003c\/strong\u003e ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Trio of Longevity-Supporting Ingredients at High Doses.\u003c\/strong\u003eNMN Pro Complete is the first and only perfectly balanced combination of NMN, Trans-Resveratrol and TMG on the market. Instead of having to take three separate supplements each day, you can now get the ideal balance of all three in one convenient serving.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNew Capsule Form.\u003c\/strong\u003e For people who don’t want to take powdered supplements, capsules are an easy, convenient, and portable way to get your NMN.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSolvent-Free.\u003c\/strong\u003e Compared to other NMN products, ours is made without any chemical solvents.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cstrong\u003eBe Aware of Fake NMN:\u003c\/strong\u003e Fraudulent companies are always attempting to out-price competitors by using NMN fake ingredients to gain market share, which is not fair to you, the consumer, or the reputable companies, like ProHealth that spends time and resources to ensure a safe and pure NMN product.\u003c\/div\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":45844902281376,"sku":"PH633","price":85.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH633_FRNT_250CC_600x600_Rev1024.png?v=1738610512"},{"product_id":"prohealth-caakg-longevity-powder-100-grams-ph696","title":"CaAKG Longevity Powder - 100 grams","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eExtend a Healthy Lifespan with Calcium AKG Longevity \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBoost cellular energy*\u003c\/li\u003e\n\u003cli\u003eOptimize mitochondrial function*\u003c\/li\u003e\n\u003cli\u003ePromote healthy aging and longevity*\u003c\/li\u003e\n\u003cli\u003eSupport bones, muscles, cognition, detoxification, and more*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/REVALIDATION_TESTING_PH696_PRHEZ-2903_Calcium_AKG_Longevity_Powder_2410015_1_2.pdf?v=1793034889\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eTargets 7 Hallmarks of Aging:\u003c\/strong\u003e AKG activates key biological pathways that help slow age-related cellular decline and promote healthy aging.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLongevity-Focused Formula:\u003c\/strong\u003e AKG has been shown to extend lifespan in animal studies by up to 50% and reduce biological age markers in humans.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e Krebs Cycle Activation:\u003c\/strong\u003e AKG fuels cellular energy production by generating NADH, supporting ATP production for improved cellular health and repair.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e Downstream Benefits:\u003c\/strong\u003e AKG metabolizes into glutamate, supporting GABA production for a balanced mind and acting as a precursor to glutathione, the body’s master detoxifier and antioxidant. Additionally, it converts into glutamine, providing fuel for gastrointestinal cells.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated Potency:\u003c\/strong\u003e Featuring a 1,000mg \"longevity dose\" of Calcium AKG. \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eEnhanced Stability:\u003c\/strong\u003e Calcium AKG is preferred over standard AKG due to its stability, bioavailability, and additional health benefits.*  \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eOptimal Absorption:\u003c\/strong\u003e Calcium AKG crosses the cell membrane more efficiently than standard AKG.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Verified three times by independent third-party laboratories to ensure unmatched purity and potency.  We proudly publish test results.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufacturing Excellence:\u003c\/strong\u003e Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eIntroducing ProHealth Calcium AKG Longevity, a revolutionary supplement that targets multiple pathways of aging. Alpha-ketoglutarate (AKG) is an essential molecule naturally produced by the body that plays a central role in energy metabolism and cellular repair. However, AKG levels decline sharply with age—dropping up to 10-fold between the ages of 40 and 80. Supplementation is necessary to maintain optimal levels as the compound is not found in food.\u003csup\u003e1*\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003eSupplementing with Calcium AKG Longevity addresses this deficiency by supplying you with a bioavailable form of AKG, designed to cross the cell membrane and fuel critical metabolic processes. It supports ATP Production, helping to enhance mitochondrial function and promote efficient energy production through the Krebs cycle. It also helps maintain DNA integrity and regulate gene expression and DNA methylation, which are key factors involved in healthy aging.*\u003cbr\u003e\u003cbr\u003eAdditionally, AKG acts as a precursor to the compound glutathione, which has antioxidant effects and helps neutralize ammonia in the body, supporting a healthy detoxification process.*\u003cbr\u003e\u003cbr\u003eIn animal studies, AKG has been shown to help extend lifespan by 10% in mice, 23% in flies, and 50% in worms.\u003csup\u003e1\u003c\/sup\u003e In human studies, AKG supplementation shows promising results for reducing biological age markers and improving overall vitality. This may be due to its effects on key pathways associated with aging, including rapamycin (mTOR) and AMP-activated protein kinase (AMPK).\u003csup\u003e3*\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eExtend a Healthy Lifespan with Calcium AKG Longevity*\u003cbr\u003e\u003cbr\u003e\u003c\/strong\u003e\u003cstrong\u003eBoosts Cellular Energy Production*\u003c\/strong\u003e \u003cbr\u003eCalcium AKG supports cellular energy by fueling the Krebs cycle, which enhances ATP production and ensures that your cells have the energy needed for optimal function. Additionally, it plays a critical role in maintaining mitochondrial efficiency, helping to combat the natural decline in energy associated with aging.\u003csup\u003e2, 4*\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003cstrong\u003eSupports Longevity Pathways*\u003c\/strong\u003e\u003cbr\u003eCalcium AKG regulates key longevity pathways, including mTOR and AMPK, to promote a healthy balance between cellular growth and repair. This regulation is essential for supporting the body’s natural processes that maintain cellular health over time. Calcium AKG also plays a role in DNA methylation, which helps regulate gene expression and supports healthy aging at the molecular level.\u003csup\u003e2, 3, 1*\u003cbr\u003e\u003cbr\u003e\u003csup\u003e\u003c\/sup\u003e\u003c\/sup\u003e\u003cstrong\u003eHelps Maintain Bone Density*\u003c\/strong\u003e\u003cbr\u003eAs a valuable source of calcium, Calcium AKG provides 15% of the daily recommended value, supporting bone strength and density. This benefit is particularly important for aging individuals, as maintaining adequate calcium levels can help reduce the risk of age-related frailty and promote long-term physical resilience and strength.\u003csup\u003e6*\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003cstrong\u003eSupports Healthy Neurotransmitters*\u003c\/strong\u003e\u003cbr\u003eCalcium AKG contributes to mental clarity and calm by supporting neurotransmitter balance. Specifically, it converts into glutamate, which is a key precursor for GABA, the brain’s calming neurotransmitter. By enhancing GABA production, Calcium AKG helps regulate the brain’s response to stress and supports a balanced mood and restful sleep.\u003csup\u003e2,3,5*\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003cstrong\u003eEncourages Detoxification and Antioxidant Production*\u003c\/strong\u003e\u003cbr\u003eCalcium AKG aids the body’s natural detoxification processes by serving as a precursor to glutathione, the body’s master antioxidant. Glutathione plays a crucial role in combating oxidative stress and supporting overall cellular health.* Additionally, Calcium AKG helps neutralize excess ammonia in the body, which can support both brain and muscle function, promoting optimal performance and resilience.\u003csup\u003e3, 5*\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003cstrong\u003eHelps Maintain Strength*\u003c\/strong\u003e\u003cbr\u003eMuch of AKG is metabolized into glutamine and other essential amino acids that can aid in the maintenance of lean muscle mass. By potentially supporting bone health, muscle function, and cellular energy production, Ca-AKG may help maintain physical strength and vitality as you age, enabling you to stay active and engaged in life's adventures.\u003csup\u003e3,8*\u003cbr\u003e\u003c\/sup\u003e\u003cbr\u003eFor athletes, studies indicate that daily doses of 3 to 4 grams of AKG, administered 1–2 times per day, may improve endurance and anaerobic capacity. Supplementation for a period of 4 to 8 weeks appears to be effective, with administration typically in powder or capsule form. For immediate performance benefits, taking AKG before exercise is commonly recommended.\u003csup\u003e7*\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003cstrong\u003eAids in Immune Function*\u003c\/strong\u003e\u003cbr\u003eGlutamine also functions as fuel for gastrointestinal and immune cells, contributing to a healthy gastrointestinal lining and immune system. Supplementation may aid in overall immune defenses, as glutamine is an important fuel for lymphocytes and macrophages, types of white blood cells that can help fight against pathogens.\u003csup\u003e5,8*\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eFeel the Difference in Your Energy with Calcium AKG Longevity\u003cbr\u003e\u003cbr\u003e\u003c\/strong\u003eReplenish what aging takes away with help from ProHealth’s Calcium AKG Longevity, which is specifically designed to restore cellular energy, enhance resilience, and promote long-term vitality. Whether you’re looking to stay active, maintain bone strength, or optimize your cellular health, this powerful supplement delivers results you can feel.*\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eOrder now and join the thousands of people who trust ProHealth for their longevity journey!\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredients:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eCalcium:\u003c\/strong\u003e Essential mineral that supports strong bones and teeth, aids muscle function, and plays a key role in nerve transmission and cellular processes.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eAlpha-Ketoglutarate (AKG):\u003c\/strong\u003e Key intermediate in the Krebs cycle, essential for cellular energy production and overall metabolic health.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e1 \u003c\/sup\u003eNaeini SH et al. Exp Gerontol. 2023;175:112154.\u003cbr\u003e\u003csup\u003e2 \u003c\/sup\u003eSandalova E et al. GeroScience. 2023;45(5):2897-2907. \u003cbr\u003e\u003csup\u003e3 \u003c\/sup\u003eGyanwali B et al. Trends Endocrinol Metab. 2022;33(2):136-146. \u003cbr\u003e\u003csup\u003e4 \u003c\/sup\u003eDemidenko O et al. Aging. 2021;13(22):24485-24499.\u003cbr\u003e\u003csup\u003e5 \u003c\/sup\u003eLiu S et al. BioMed Res Int. 2018;2018:3408467. \u003cbr\u003e\u003csup\u003e6 \u003c\/sup\u003eTrailokya A et al. Calcium and Calcium Salts. \u003cbr\u003e\u003csup\u003e7 \u003c\/sup\u003eXu M et al. Nutrients. 2024;16(22):3968. \u003cbr\u003e\u003csup\u003e8 \u003c\/sup\u003eWu N et al. Biomol Ther. 2016;24(1):1-8.\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\" style=\"height: 275.333px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003eServing Size: 1 Scoop (1.02 g)\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003eServings Per Container: 100\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"font-weight: bold; height: 19.6px;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eCalcium (from 1000 mg of calcium Alpha-Ketoglutarate)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e180 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e14%††\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eCalcium Alpha-Ketoglutarate\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e1000 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\" align=\"right\"\u003e\u003cbr\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003e††Percent Daily Value (DV) based on 2,000 calorie diet\u003cbr\u003e†Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.11.24\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake one (1) scoop in the morning with or without food, or as directed by your healthcare professional.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":52261665767584,"sku":"PH696","price":49.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH696_FRNT_250CC_Jar_600x600_REV-1124.png?v=1739481900"},{"product_id":"prohealth-nicotinamide-riboside-pterostilbene-30-capsules-ph710","title":"Nicotinamide Riboside + Pterostilbene - 30 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003eNicotinamide riboside (NR), an advanced form of vitamin B3 (niacin), has proven to be one of the most promising supplements to promote longevity and healthy aging. By functioning as an NAD+ precursor, NR has been proven to significantly increase NAD+ levels in the body, thus promoting heart, brain, metabolic, and cellular health. Pterostilbene is a powerful antioxidant compound that has been shown to activate sirtuins (longevity genes), amplifying the longevity-promoting effects of NR.\u003c\/p\u003e\n\u003ch2\u003eNR + Pterostilbene\u003c\/h2\u003e\n\u003cul\u003e\n\u003cli\u003eSupports longevity by increasing NAD+ levels and activating sirtuins\u003c\/li\u003e\n\u003cli\u003eEnhances cellular health by promoting DNA repair and reducing oxidative stress\u003c\/li\u003e\n\u003cli\u003ePromotes heart health by supporting healthy blood flow\u003c\/li\u003e\n\u003cli\u003eProtects the brain from age-related functional decline\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH710_-_COA_Brighton_LOT_26033_2025.09.10_2.pdf?v=1757958063\" target=\"_blank\"\u003eView Certificate of Analysis »\u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003ch3\u003eResearch-Supported Benefits:\u003c\/h3\u003e\n\u003cp\u003e\u003cstrong\u003ePromotes Longevity. \u003c\/strong\u003eNicotinamide Riboside promotes longevity by increasing levels of NAD+ in the body. NAD+ levels decline with age, contributing to accelerated cellular aging and health decline. Research shows that increasing NAD+ levels in aged animals extends lifespan. (1) Pterostilbene supports longevity by activating sirtuins, which are commonly referred to as \"longevity genes\". Animal studies show that activating sirtuins extends lifespan and healthspan. (2)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eSupports Cellular Health.\u003c\/strong\u003e By increasing NAD+ levels, NR aids in facilitating DNA repair. (3) DNA damage is associated with decreased longevity and increased risk for age-related health decline, highlighting the importance of the DNA repair process. Due to its antioxidant potential, pterostilbene offers additional protection for cellular health by reducing oxidative damage, a key contributor to cellular aging. (4)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eEnhances Heart Health. \u003c\/strong\u003eResearch shows that NR enhances heart health by reducing stiffness of the arteries and supporting healthy blood flow. (5) Aortic stiffness contributes to blood pressure dysregulation and increased cardiac risk, making the reduction of aortic stiffness critical to maintaining heart health. Animal studies also show pterostilbene exhibits cardio-protective effects by reducing oxidative stress of heart tissue. (6)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eProtects Against Cognitive Decline. \u003c\/strong\u003eNAD+ is critical to maintaining mitochondrial health of brain cells. A decline of NAD+ levels research suggests that reduced NAD+ levels contribute to many of the hallmarks of brain aging. By increasing NAD+ levels and aiding in the regulation of inflammatory levels, Nicotinamide Riboside shows promise in supporting healthy brain aging and cognitive function. (7) Pterostilbene further supports healthy brain aging by activating sirt-1 and improving synaptic plasticity, a vital biological process related to memory and learning. (8)\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e1. Fang EF, Lautrup S, Hou Y, et al. NAD+ in Aging: Molecular Mechanisms and Translational Implications. Trends Mol Med. 2017;23(10):899-916. doi:10.1016\/j.molmed.2017.08.001 \u003cbr\u003e\u003cbr\u003e2. Grabowska W, Sikora E, Bielak-Zmijewska A. Sirtuins, a promising target in slowing down the ageing process. Biogerontology. 2017;18(4):447-476. doi:10.1007\/s10522-017-9685-9 \u003cbr\u003e\u003cbr\u003e3. Wilk A, Hayat F, Cunningham R, et al. Extracellular NAD+ enhances PARP-dependent DNA repair capacity independently of CD73 activity. Sci Rep. 2020;10(1):651. Published 2020 Jan 20. doi:10.1038\/s41598-020-57506-9 \u003cbr\u003e\u003cbr\u003e4. Nagarajan S, Mohandas S, Ganesan K, Xu B, Ramkumar KM. New Insights into Dietary Pterostilbene: Sources, Metabolism, and Health Promotion Effects. Molecules. 2022;27(19):6316. Published 2022 Sep 25. doi:10.3390\/molecules27196316 \u003cbr\u003e\u003cbr\u003e5. Martens CR, Denman BA, Mazzo MR, et al. Chronic nicotinamide riboside supplementation is well-tolerated and elevates NAD+ in healthy middle-aged and older adults. Nat Commun. 2018;9(1):1286. Published 2018 Mar 29. doi:10.1038\/s41467-018-03421-7 \u003cbr\u003e\u003cbr\u003e6. Kosuru R, Kandula V, Rai U, Prakash S, Xia Z, Singh S. Pterostilbene Decreases Cardiac Oxidative Stress and Inflammation via Activation of AMPK\/Nrf2\/HO-1 Pathway in Fructose-Fed Diabetic Rats. Cardiovasc Drugs Ther. 2018;32(2):147-163. doi:10.1007\/s10557-018-6780-3 \u003cbr\u003e\u003cbr\u003e7. Lee HJ, Yang SJ. Supplementation with Nicotinamide Riboside Reduces Brain Inflammation and Improves Cognitive Function in Diabetic Mice. Int J Mol Sci. 2019;20(17):4196. Published 2019 Aug 27. doi:10.3390\/ijms20174196 \u003cbr\u003e\u003cbr\u003e8. Michán S, Li Y, Chou MM, et al. SIRT1 is essential for normal cognitive function and synaptic plasticity. J Neurosci. 2010;30(29):9695-9707. doi:10.1523\/JNEUROSCI.0027-10.2010 \u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-how-it-work-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003eNicotinamide Riboside (NR) and pterostilbene represent a powerful 1-2 combo in longevity supplements due to their respective ability to increase NAD+ levels and activate sirtuins.\u003c\/li\u003e\n\u003cli\u003eNAD+ functions as the fuel for sirtuins, which then activate defensive enzymes to fight aging.\u003c\/li\u003e\n\u003cli\u003eNAD+ levels decline with age, with an estimated 50% decline in NAD+ levels by age 50\u003c\/li\u003e\n\u003cli\u003eThis decline in NAD+ production reduces the ability of sirtuins to perform their anti-aging repair effects.\u003c\/li\u003e\n\u003cli\u003eNR and pterostilbene further support healthy aging by improving mitochondrial health, supporting cardiovascular function, and protecting against symptoms of brain aging.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\"\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003cth colspan=\"3\" style=\"font-size: 11pt; font-weight: bold;\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"2\" class=\"smalltext\" style=\"font-weight: bold;\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003eNR (as Nicotinamide Riboside \u003cbr\u003e  Hydrogen Malate)\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e250 mg\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd class=\"smalltext\"\u003ePterostilbene\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e40 mg\u003cbr\u003e\n\u003c\/td\u003e\n\u003ctd class=\"smalltext\" style=\"white-space: nowrap;\" align=\"right\"\u003e†\u003cbr\u003e\n\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd colspan=\"3\" class=\"smalltext\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.07.25\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eHypromellose (capsule), rice flour.\u003cstrong\u003e \u003c\/strong\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE:\u003c\/strong\u003e Take one (1) capsule per day, with or without food, preferably in the morning.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION:\u003c\/strong\u003e For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"summary-copy\"\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUnique Formulation. \u003c\/strong\u003eProHealth’s NR + Pterostilbene was specifically formulated to reduce symptoms of age-related health decline. By combining these two complimentary ingredients, this formula amplifies the effect of either ingredient if taken alone.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eQuality Manufacturing Practices.\u003c\/strong\u003e All of our products are manufactured in an FDA-registered, GMP-certified facility.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eThird-Party Tested in the USA.\u003c\/strong\u003e Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":52366405468320,"sku":"PH710","price":29.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH710_175MCC_FRNT_600x600_REV1124.png?v=1744215932"},{"product_id":"prohealth-full-spectrum-urolithin-a-60-capsules-ph694","title":"Full Spectrum Urolithin A - 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eUrolithin A: The Gold Standard Longevity Molecule \u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eBoost Urolithin A levels*\u003csup\u003e1-2\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eDiminish oxidative stress*\u003csup\u003e3-5\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eEnhance cellular health*\u003csup\u003e1,6-7\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eSupport youthful aging and longevity*\u003csup\u003e1,3,7-11\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca style=\"color: #0000ff;\" rel=\"noopener noreferrer\" href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH694_-_COA_Brighton_LOT_A26H041_2026.10.21_2.pdf?v=1792681465\" target=\"_blank\"\u003eView Certificate of Analysis \u003c\/a\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003eOur full spectrum formula delivers a clinically supported dose of Urolithin A, paired with its natural precursors in polyphenol-rich extracts from pomegranate and red muscadine grapes. Urolithin A directly supports levels of this key longevity molecule, while the fruits enhance gut metabolism to further amplify Urolithin A production—providing a powerful “double boost” to unlock its full potential.* \u003csup\u003e1-3,12-13\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Spectrum Blend:\u003c\/strong\u003e Combines pure Urolithin A with powerful fruit extracts that help boost Urolithin A production in your body.*\u003csup\u003e1-2\u003c\/sup\u003e \u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBio-Identical Support:\u003c\/strong\u003e Urolithin A is a naturally occurring “postbiotic” produced by your gut during the digestion of polyphenols (ellagic acid and ellagitannins) found in foods.*\u003csup\u003e10\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eGut-Boosting Polyphenols:\u003c\/strong\u003e These prebiotic-like compounds nourish your gut microbiome, promoting the growth of Urolithin A-producing bacteria.*\u003csup\u003e12-13\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eBridge the Microbiome Gap:\u003c\/strong\u003e Not everyone has the gut bacteria needed to produce Urolithin A, but our unique full-spectrum formula ensures that you—along with everyone else—can benefit from its powerful effects.*\u003csup\u003e8-9\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhy Choose ProHealth?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated:\u003c\/strong\u003e Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*\u003cbr\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eFull Transparency:\u003c\/strong\u003e In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eManufactured in the USA:\u003c\/strong\u003e Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eUrolithin A is a bioavailable metabolite produced in the colon when gut microbiota metabolizes polyphenols (ellagitannins and ellagic acid) from a healthy diet. As we age, our ability to convert these polyphenols into Urolithin A declines, influenced by factors like gut microbiome composition, diet, health, and genetics. A significant portion of the population struggles to efficiently convert polyphenols into Urolithin A.\u003csup\u003e2,8-10\u003c\/sup\u003e\u003cbr\u003e\u003cbr\u003eSupplemental Urolithin A bypasses these challenges, providing benefits regardless of age, microbiome, or genetics. It enters the bloodstream and reaches tissues and cells that need it most, activating key pathways for healthy aging.*\u003csup\u003e2,9\u003c\/sup\u003e \u003cbr\u003e\u003cbr\u003eWhile supplemental Urolithin A provides direct systemic support, diet-derived precursors primarily benefit the gut microbiome. Research shows that dietary polyphenols can promote intestinal wellness by supporting Urolithin A-producing bacteria, leading to increased Urolithin A production. To optimize these effects, we’ve incorporated concentrated polyphenol extracts into our full-spectrum formula.*\u003csup\u003e12-13\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eTarget Core Longevity Pathways* \u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eWhether sourced from supplementation or naturally produced in the gut, Urolithin A efficiently enters the bloodstream and reaches cells throughout the body, where it influences multiple metabolic pathways linked to longevity:\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eAMPK:\u003c\/strong\u003e Fuels energy production and metabolism.*\u003csup\u003e3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003emTOR:\u003c\/strong\u003e Supports cell repair and regeneration.*\u003csup\u003e1,3,10\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSIRT1:\u003c\/strong\u003e Protects DNA and combats cellular senescence.*\u003csup\u003e1-2,14\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eNF-kB:\u003c\/strong\u003e Impacts inflammation, a key factor in aging.*\u003csup\u003e1,3,8-10\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eUrolithin A has quickly become one of the most exciting longevity molecules, targeting aging at its cellular core while activating multiple longevity pathways. Clinically validated, it stands as one of the most promising compounds for extending healthspan and preserving vitality throughout the aging process.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eFeel the Difference with ProHealth Full Spectrum Urolithin A \u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eElevate your longevity with a dual boost of Urolithin A and its natural precursors. Expertly formulated by doctors, this advanced formula is designed to maximize the benefits of Urolithin A, delivering full-spectrum support for your health, vitality, and longevity.*\u003csup\u003e1-3,12,13\u003c\/sup\u003e\u003cstrong\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eOrder now and join the 200,000+ people who trust ProHealth Full Spectrum Urolithin A for their cellular health!\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredients:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eUrolithin A:\u003c\/strong\u003e A powerful gut-derived compound produced by the microbiome when it metabolizes ellagic acid from foods like pomegranates, berries, and walnuts.*\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003ePomegranate Extract:\u003c\/strong\u003e A potent superfruit and key precursor to Urolithin A, standardized to 30% punicalagins, the primary polyphenolic compound responsible for pomegranate’s health benefits.*\u003csup\u003e15-16\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eRed Muscadine Grape Extract:\u003c\/strong\u003e A nutrient-dense fruit known for its abundance of polyphenolic compounds such as resveratrol and ellagic acid.*\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003csup\u003e1 \u003c\/sup\u003eLiu Y et al. \u003cem\u003eNutrients\u003c\/em\u003e. 2024;16(19):3305. \u003cbr\u003e\u003csup\u003e2 \u003c\/sup\u003eGarcía-Villalba R et al. \u003cem\u003eMol Aspects Med.\u003c\/em\u003e 2023;89:101109.\u003cbr\u003e\u003csup\u003e3 \u003c\/sup\u003eZhao H et al. \u003cem\u003eNutrients.\u003c\/em\u003e 2023;15(20):4441.\u003cbr\u003e\u003csup\u003e4 \u003c\/sup\u003eZhao et al. \u003cem\u003eJ Int Soc Sports Nutr.\u003c\/em\u003e 2024;21(1):2419388.\u003cbr\u003e\u003csup\u003e5 \u003c\/sup\u003eVerdú D et al. \u003cem\u003eAntioxidants (Basel)\u003c\/em\u003e. 2023;12(11):1991. \u003cbr\u003e\u003csup\u003e6 \u003c\/sup\u003eAndreux PA et al. \u003cem\u003eNat Metab.\u003c\/em\u003e 2019;1(6):595-603.  \u003cbr\u003e\u003csup\u003e7 \u003c\/sup\u003eGarcía-Villalba R et al. \u003cem\u003eMol Aspects Med.\u003c\/em\u003e 2023;89:101109. \u003cbr\u003e\u003csup\u003e8 \u003c\/sup\u003eD’Amico D et al. \u003cem\u003eTrends Mol Med\u003c\/em\u003e. 2021;27(7):687-699. \u003cbr\u003e\u003csup\u003e9 \u003c\/sup\u003eKuerec AH et al. \u003cem\u003eAgeing Res Rev.\u003c\/em\u003e 2024;100:102406.\u003cbr\u003e\u003csup\u003e10 \u003c\/sup\u003eShetty SS et al. Beni-Suef Univ J Basic Appl Sci. 2024;13(1):31.\u003cbr\u003e\u003csup\u003e11 \u003c\/sup\u003eKubota D et al. \u003cem\u003eNutrients.\u003c\/em\u003e 2024;16(19):3369.  \u003cbr\u003e\u003csup\u003e12 \u003c\/sup\u003eChen P et al. \u003cem\u003eJ Integr Neurosci.\u003c\/em\u003e 2023;22(5):113. \u003cbr\u003e\u003csup\u003e13 \u003c\/sup\u003eAlves-Santos AM et al. \u003cem\u003eJ Funct Foods.\u003c\/em\u003e 2020;74:104169.\u003cbr\u003e\u003csup\u003e14 \u003c\/sup\u003eShi PZ et al. World J Stem Cells. 2021;13(12):1928-1946\u003cbr\u003e\u003csup\u003e15 \u003c\/sup\u003eStockton A. \u003cem\u003eEC Nutrition.\u003c\/em\u003e 2015;2(4):396-411. \u003cbr\u003e\u003csup\u003e16 \u003c\/sup\u003eStockton A et al. \u003cem\u003eJ Nutr Sci.\u003c\/em\u003e 2017;6:e39.\u003c\/p\u003e\n\u003cstrong\u003e\u003cstrong\u003e\u003c\/strong\u003e \u003c\/strong\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable width=\"100%\" cellspacing=\"2\" cellpadding=\"0\" border=\"0\" style=\"height: 243.333px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 29.9667px;\"\u003e\n\u003cth style=\"font-size: 11pt; font-weight: bold; height: 29.9667px;\" colspan=\"3\" align=\"left\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.0333px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 29.0333px;\"\u003eServing Size: 2 Capsules\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.0333px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 29.0333px;\"\u003eServings Per Container: 30\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29.0333px;\"\u003e\n\u003ctd style=\"font-weight: bold; height: 29.0333px;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 29.0333px;\" class=\"smalltext\" align=\"right\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 48.6333px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 48.6333px;\"\u003eStanYouth® Urolithin A\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 48.6333px;\" class=\"smalltext\" align=\"right\"\u003e500 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 48.6333px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 48.6333px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 48.6333px;\"\u003ePomanox® Pomegranate Fruit\u003cbr\u003e  Extract (30% punicalagins)\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 48.6333px;\" class=\"smalltext\" align=\"right\"\u003e250 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 48.6333px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 48.6333px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 48.6333px;\"\u003eMuscadine Grape Skin and\u003cbr\u003e  Seed Extract\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 48.6333px;\" class=\"smalltext\" align=\"right\"\u003e100 mg\u003c\/td\u003e\n\u003ctd style=\"white-space: nowrap; height: 48.6333px;\" class=\"smalltext\" align=\"right\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 29px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 29px;\"\u003e† Daily Value (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\nREV.11.25\u003cbr\u003e\u003cbr\u003eStanYouth® is a registered trademark of Bonerge Lifescience Corp. Pomanox® is a registered trademark of Euromed S.A.\u003cbr\u003e\u003cbr\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eMicrocrystalline cellulose, hypromellose (capsule), bamboo extract.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake two (2) capsules per day, preferably with food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN.\u003c\/strong\u003e Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":52380263415968,"sku":"PH694","price":79.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH694_175CC_FRNT_600x600_REV-0125.png?v=1743542451"},{"product_id":"prohealth-sirtuin-1-activator-60-capsules-ph665","title":"Sirtuin 1 Activator - 60 capsules","description":"\u003cdiv class=\"product-benefits-copy\"\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eSwitch On the Longevity Gene\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eActivates and supports SIRT1*\u003csup\u003e1-7\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003ePromotes healthy aging at the cellular level*\u003csup\u003e2,3,8-11\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eStrengthens the body’s antioxidant network*\u003csup\u003e12\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eHelps maintain metabolic and inflammatory health*\u003csup\u003e13\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003eBoosts mitochondrial biogenesis and energy output*\u003csup\u003e1,3\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cspan style=\"color: #0000ff;\"\u003e\u003ca href=\"https:\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH665_-_COA_Brighton_LOT_26058_2025-11-11_2.pdf?v=1764179037\" rel=\"noopener noreferrer\" style=\"color: #0000ff;\" target=\"_blank\"\u003eView Certificate of Analysis\u003c\/a\u003e\u003cbr\u003e\u003cbr\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe Science of SIRT1 \u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cbr\u003eInside every cell is a guardian protein called sirtuin 1 (SIRT1), short for Silent Information Regulator. It helps decide which parts of your DNA stay quiet and which stay active, helping cells adapt to stress, maintain energy efficiency, and resist the effects of aging.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eCommonly known as the \"longevity switch,\" SIRT1 is involved in DNA repair, the removal of damaged cellular components, and the optimization of energy use. As we age, SIRT1 activity naturally declines due to factors such as oxidative stress, poor diet, disrupted sleep, and environmental challenges. This reduction is linked to diminished cellular resilience and many of the classic signs of aging.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003eThe good news is that certain food compounds can help support SIRT1 function. Plant-derived polyphenols such as resveratrol (from red grapes) and pterostilbene (from blueberries) are among the best-studied for their ability to activate SIRT1 and promote healthy cellular aging. These compounds mimic calorie restriction at the molecular level, helping to reactivate SIRT1 and restore youthful gene expression patterns. By boosting SIRT1 activity, they help shift cells into a protective, repair-focused state, supporting the body’s natural defenses as we age.*\u003csup\u003e1-7\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhy Resveratrol + Pterostilbene Work Better Togethe\u003cbr\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003eResveratrol is well-known for supporting SIRT1, but the body clears it fast. The liver converts most of it into inactive metabolites within minutes. Blood levels fall quickly, so only a limited amount reaches cells. The effect on SIRT1 is meaningful, yet short-lived.*\u003csup\u003e1-3,5-7\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003ePterostilbene shifts the profile. It is a close relative of resveratrol with two methyl groups that improve its performance.\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003eUp to 4× higher oral bioavailability*\u003c\/li\u003e\n\u003cli\u003eGreater lipophilicity for superior cellular penetration*\u003c\/li\u003e\n\u003cli\u003eSignificantly longer half-life in the body (up to 7× longer than resveratrol)*\u003csup\u003e4,14-16\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003eWhen used together in a balanced ratio, the two ingredients work in sequence. Resveratrol supports a fast SIRT1 response. Pterostilbene keeps that response active for a longer period due to its greater stability. This provides steadier sirtuin pathway support than resveratrol alone.*\u003csup\u003e1-7,14-16\u003cbr\u003e\u003cbr\u003e\u003c\/sup\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eWhat Makes Ours Better?\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003e4:1 Polyphenol Complex:\u003c\/strong\u003e Balanced to reflect bioavailability differences between resveratrol and pterostilbene.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eClinically Studied Forms:\u003c\/strong\u003e Includes the active trans form of resveratrol and pterostilbene for consistency and purity.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eLongevity Pathway Support:\u003c\/strong\u003e Engages SIRT1, AMPK and PGC-1α pathways linked to mitochondrial function and cellular upkeep.*\u003csup\u003e1-7\u003c\/sup\u003e\n\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eMinimalist Formula:\u003c\/strong\u003e Uses only active polyphenols for a straightforward, clean profile.*\u003cbr\u003e\u003cbr\u003e\n\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eThe ProHealth Difference\u003c\/strong\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eDoctor-Formulated:\u003c\/strong\u003e Developed by our in-house science team in collaboration with leading wellness experts.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eTriple Lab Tested:\u003c\/strong\u003e Verified three times by independent labs for purity and potency.\u003c\/li\u003e\n\u003cli\u003e \u003cstrong\u003eFull Transparency:\u003c\/strong\u003e Third-party test results published online for complete confidence.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eUSA Manufactured:\u003c\/strong\u003e Proudly manufactured in the USA in FDA-registered, GMP-certified facilities since 1988.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003e100-Day Risk-Free Guarantee:\u003c\/strong\u003e If you’re not fully satisfied, we’ll refund your purchase in full.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eA Word from our Chief Science Officer\u003cbr\u003e\u003cbr\u003e\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\"Resveratrol brought SIRT1 into the spotlight, but bioavailability has always limited its potential. By combining it with pterostilbene, we’re matching kinetics with biology — ensuring both rapid activation and sustained support of this key longevity pathway.\"\u003cbr\u003e\u003cbr\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong style=\"font-size: 1.1em;\"\u003eIngredient Info\u003c\/strong\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eTrans-Resveratrol:\u003c\/strong\u003e The active, naturally occurring form of resveratrol that supports key cellular pathways involved in healthy aging.*\u003cbr\u003e\u003cstrong\u003eTrans-Pterostilbene:\u003c\/strong\u003e A lipophilic stilbene that engages the SIRT1 pathway and complements resveratrol for steady cellular support.*\u003c\/p\u003e\n\u003cp\u003e\u003cstrong\u003eReferences:\u003c\/strong\u003e\u003c\/p\u003e\n\u003col\u003e\n\u003cli\u003eDella Vedova L et al. \u003cem\u003ePharmaceuticals (Basel)\u003c\/em\u003e. 2025;18(2):138.\u003c\/li\u003e\n\u003cli\u003eZhou DD et al. \u003cem\u003eSubcell Biochem\u003c\/em\u003e. 2024;107:183-203.\u003c\/li\u003e\n\u003cli\u003eLi YR et al. \u003cem\u003eBiofactors\u003c\/em\u003e. 2018;44(1):69-82.\u003c\/li\u003e\n\u003cli\u003eWood JG et al. \u003cem\u003eNature\u003c\/em\u003e. 2004;430(7000):686-689.\u003c\/li\u003e\n\u003cli\u003eKuršvietienė L et al. \u003cem\u003eMedicina\u003c\/em\u003e. 2016;52(3),148-155.\u003c\/li\u003e\n\u003cli\u003eLakshminarasimhan M et al. \u003cem\u003eAging (Albany NY)\u003c\/em\u003e. 2013;5(3),151.\u003c\/li\u003e\n\u003cli\u003eBorra MT et al. \u003cem\u003eJ Biol Chem\u003c\/em\u003e. 2005;280(17),17187-17195.\u003c\/li\u003e\n\u003cli\u003eThaung Zaw JJ et al. \u003cem\u003eClin Nutr\u003c\/em\u003e. 2021;40(3):820-829.\u003c\/li\u003e\n\u003cli\u003eThaung Zaw JJ et al. \u003cem\u003eMenopause.\u003c\/em\u003e 2021;28(1):40-49.\u003c\/li\u003e\n\u003cli\u003eWong RH et al. \u003cem\u003eJ Bone Miner Res\u003c\/em\u003e. 2020;35(11):2121-2131.\u003c\/li\u003e\n\u003cli\u003eThaung Zaw JJ et al. \u003cem\u003eNutrients\u003c\/em\u003e. 2020;12(3):828.\u003c\/li\u003e\n\u003cli\u003eChan EWC et al. \u003cem\u003eJ Appl Pharm Sci.\u003c\/em\u003e 2019;9(7):124-129.\u003c\/li\u003e\n\u003cli\u003eDella Vedova L et a. \u003cem\u003ePharmaceuticals (Basel)\u003c\/em\u003e. 2025;18(2):138.\u003c\/li\u003e\n\u003cli\u003eWang P, Sang S. \u003cem\u003eBiofactors.\u003c\/em\u003e 2018;44(1):16-25.\u003c\/li\u003e\n\u003cli\u003eRiche DM et al.  \u003cem\u003eJ Toxicol\u003c\/em\u003e. 2013;2013:463595.\u003c\/li\u003e\n\u003cli\u003eKapetanovic IM et al. \u003cem\u003eCancer Chemother Pharmacol.\u003c\/em\u003e 2011;68(3):593-601.\u003c\/li\u003e\n\u003c\/ol\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"product-label-copy\"\u003e\n\u003ctable border=\"0\" cellpadding=\"0\" cellspacing=\"2\" width=\"100%\" style=\"height: 275.333px;\"\u003e\n\u003ctbody\u003e\n\u003ctr style=\"height: 20.5333px;\"\u003e\n\u003cth align=\"left\" style=\"font-size: 11pt; font-weight: bold; height: 20.5333px;\" colspan=\"3\"\u003eSupplement Facts\u003c\/th\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003eServing Size: 1 Capsule\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 19.6px;\"\u003eServings Per Container: 60\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd style=\"font-weight: bold; height: 19.6px;\" class=\"smalltext\" colspan=\"2\"\u003eAmount Per Serving\u003c\/td\u003e\n\u003ctd align=\"right\" class=\"smalltext\" style=\"white-space: nowrap; height: 19.6px;\"\u003e\u003cstrong\u003e%DV\u003c\/strong\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eVeri-te® Trans-Resveratrol\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\"\u003e200 mg\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 19.6px;\"\u003e\n\u003ctd class=\"smalltext\" style=\"height: 19.6px;\"\u003eTrans-Pterostilbene\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\"\u003e50 mg\u003c\/td\u003e\n\u003ctd align=\"right\" style=\"white-space: nowrap; height: 19.6px;\" class=\"smalltext\"\u003e†\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr style=\"height: 39.2px;\"\u003e\n\u003ctd class=\"smalltext\" colspan=\"3\" style=\"height: 39.2px;\"\u003e† Percent Daily Values (DV) not established\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003cbr\u003e\n\u003cp\u003eREV.10.25\u003c\/p\u003e\nVeri-te® is a registered trademark of the Lallemand group.\n\u003cul\u003e\n\u003cli\u003e\n\u003cstrong\u003eOTHER INGREDIENTS: \u003c\/strong\u003eRice flour, hypromellose (capsule).\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eSUGGESTED DAILY USE: \u003c\/strong\u003eTake one (1) capsule per day with food.\u003c\/li\u003e\n\u003cli\u003e\n\u003cstrong\u003eCAUTION: \u003c\/strong\u003eFor use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. \u003cstrong\u003eKEEP OUT OF REACH OF CHILDREN\u003c\/strong\u003e. Store in a cool and dry place after opening.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"ProHealth Wholesale","offers":[{"title":"Default Title","offer_id":53047126982816,"sku":"PH665","price":39.95,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0507\/7588\/3936\/files\/PH665_175CC_FRNT_600x600-REV-1025.png?v=1763681455"}],"url":"https:\/\/wholesale.prohealth.com\/collections\/ampk-activation.oembed","provider":"ProHealth Wholesale","version":"1.0","type":"link"}